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Our purpose is to analyze the changes induced in the posterior corneal surface in patients implanted with intracorneal ring segments for treatment of keratoconus. Patients are assessed with corneal imaging device preoperatively and at 1, 3, 6 and 12 months postoperatively.
Procedure: Femtosecond laser assisted implantation of intracorneal ring segments in keratoconus patients Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refraction, keratometric (K) readings of the anterior and posterior surface, corneal asphericity (Q value) of the anterior and posterior surface, and anterior and posterior elevations are evaluated using a corneal imaging device preoperatively and at 1, 3, 6 and 12 months after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study group | Experimental | Intracorneal ring segments are implanted for treatment of keratoconus, and posterior corneal surface is assessed preoperatively and postoperatively. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intracorneal ring segment implantation | Procedure | Surgical procedure for keratoconus treatment. A tunnel is created in the corneal stroma with femtosecond laser and ring segments are implanted in the corneal stroma |
| Measure | Description | Time Frame |
|---|---|---|
| Posterior corneal astigmatism | It is measured by corneal imaging device preoperatively and postoperatively | Baseline to 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Acuity | It is measured by Snellen Chart Acuity | Baseline to 12 months |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University | Cairo | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22410615 | Background | Sogutlu E, Pinero DP, Kubaloglu A, Alio JL, Cinar Y. Elevation changes of central posterior corneal surface after intracorneal ring segment implantation in keratoconus. Cornea. 2012 Apr;31(4):387-95. doi: 10.1097/ICO.0b013e31822481df. | |
| 29256982 | Background | Muftuoglu O, Aydin R, Kilic Muftuoglu I. Persistence of the Cone on the Posterior Corneal Surface Affecting Corneal Aberration Changes After Intracorneal Ring Segment Implantation in Patients With Keratoconus. Cornea. 2018 Mar;37(3):347-353. doi: 10.1097/ICO.0000000000001492. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | May 30, 2018 | Jan 18, 2021 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
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| 23806046 | Background | Rho CR, Na KS, Yoo YS, Pandey C, Park CW, Joo CK. Changes in anterior and posterior corneal parameters in patients with keratoconus after intrastromal corneal-ring segment implantation. Curr Eye Res. 2013 Aug;38(8):843-50. doi: 10.3109/02713683.2013.788723. Epub 2013 Apr 22. |