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The primary aim of the study is to quantify abdominal motion in order to optimise MR imaging. The study will compare three-motion management strategies a) free-breathing, b) using an abdominal compression belt and c) using MRI-compatible visually guided breath-holds.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Free-breathing versus Compression | This cohort of volunteers and patients will undergo imaging on the MR-Linac investigating free-breathing motion, and comparing it to motion using an abdominal compression device. |
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| Free-breathing versus Breath-holding | This cohort of volunteers and patients will undergo imaging on the MRSim investigating free-breathing motion and comparing it to visually-guided breath-hold motion (and reproducibility). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Compression belt | Device | The abdominal belt is fastened around the lower abdomen and inflated (like an inner tube) to apply pressure to the belly and reduce the motion associated with respiration (breathing) |
| Measure | Description | Time Frame |
|---|---|---|
| MRI Motion Management SOP | Development and implementation of an MRI protocol suitable for organ motion characterisation for the abdomen. Determination of the benefit of motion management strategies for abdominal radiotherapy. | through study completion, approximately 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Quantification of motion | Quantification of intra-abdominal inter and intra-fraction motion with and without abdominal compression and visually guided breath holds using MR imaging. Comparative analysis of comparable treatment plans with and without abdominal compression and visually guided breath holds on relevant treatment planning software for PBT and MRL. Development of process to evaluate patient compliance when using a commercial available abdominal compression belt and visually guided breath-hold. |
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Inclusion Criteria:
Healthy volunteers
Patient Volunteers
Exclusion Criteria:
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Patients or staff at The Christie NHS Foundation Trust
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Christie NHS Foundation Trust | Manchester | Greater Manchester | M20 4BX | United Kingdom |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
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| Visual Guided Breath-hold | Other | A small tracer will be place on the lower abdomen that will feedback to a computer screen that will have graphics to show you if the participant is in breath-hold or not. |
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| through study completion, approximately 6 months |