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The first Intestinal Vascular Emergency Unit (SURVI), with the institutional support of AP-HP, opened on 4 January 2016, within the Paris-Nord Val de Seine University Hospital Group. This intensive care is dedicated to the management of mesenteric ischemias (acute mesenteric ischemias, chronic mesenteric ischemias) and Intestinal Vascular Diseases Without Ischemia. The organisation of this type of dedicated centre, combining advances in resuscitation, interventional radiology and knowledge of intestinal vascular diseases, has led to a radical change in the prognosis for acute mesenteric ischaemia with a survival rate of over 80% and an intestinal resection rate of less than 40%.
Acute mesenteric ischaemia (AMI) is characterised by the combination of digestive distress and vascular insufficiency: occlusive (thrombosis, embolism, arterial, venous) or non-occlusive (low flow or vasospasm). The vital prognosis is catastrophic in the absence of treatment (the mortality rate of an intestinal infarction is almost 100% without treatment), and the functional and anatomical after-effects are major for the survivors.
Many intestinal vascular diseases have been identified as providing acute and chronic mesenteric ischaemia. The nosological framework of these diseases is broad, ranging from constitutional diseases of the vessels (collagenosis, arcuate ligament syndrome) to acquired diseases of a thrombophilic, cardiac, degenerative, autoimmune, iatrogenic, traumatic nature... The rarity of these diseases (with the exception of atherosclerotic disease, the incidence of which is increasing with the ageing of the population) makes their level of knowledge insufficient.
The natural history of vascular diseases without ischaemia (rate of acute and chronic mesenteric ischaemia, mortality rate, resection rate...) is currently not described.
The construction of a longitudinal observational cohort is necessary for the prevalence of ischaemic complications and predictive factors.
The first Intestinal Vascular Emergency Unit (SURVI), with the institutional support of AP-HP, opened on 4 January 2016, within the Paris-Nord Val de Seine University Hospital Group. This intensive care is dedicated to the management of mesenteric ischemias (acute mesenteric ischemias, chronic mesenteric ischemias) and Intestinal Vascular Diseases Without Ischemia. The organisation of this type of dedicated centre, combining advances in resuscitation, interventional radiology and knowledge of intestinal vascular diseases, has led to a radical change in the prognosis for acute mesenteric ischaemia with a survival rate of over 80% and an intestinal resection rate of less than 40%.
Acute mesenteric ischaemia (AMI) is characterised by the combination of digestive distress and vascular insufficiency: occlusive (thrombosis, embolism, arterial, venous) or non-occlusive (low flow or vasospasm). The vital prognosis is catastrophic in the absence of treatment (the mortality rate of an intestinal infarction is almost 100% without treatment), and the functional and anatomical after-effects are major for the survivors.
Many intestinal vascular diseases have been identified as providing acute and chronic mesenteric ischaemia. The nosological framework of these diseases is broad, ranging from constitutional diseases of the vessels (collagenosis, arcuate ligament syndrome) to acquired diseases of a thrombophilic, cardiac, degenerative, autoimmune, iatrogenic, traumatic nature... The rarity of these diseases (with the exception of atherosclerotic disease, the incidence of which is increasing with the ageing of the population) makes their level of knowledge insufficient.
The natural history of vascular diseases without ischaemia (rate of acute and chronic mesenteric ischaemia, mortality rate, resection rate...) is currently not described.
The construction of a longitudinal observational cohort is necessary for the prevalence of ischaemic complications and predictive factors.
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| Measure | Description | Time Frame |
|---|---|---|
| mortality of Intestinal Ischemia | To study the prognosis of Intestinal (acute and chronic) Ischemia and Vascular Diseases (IIVD) at 1 year in terms of mortality. | 1 year |
| mortality of Intestinal Ischemia | To study the prognosis of Intestinal (acute and chronic) Ischemia and Vascular Diseases (IIVD) at 5 years in terms of mortality. | 5 years |
| Vascular Diseases (IIVD) | To study the prognosis of Intestinal (acute and chronic) Ischemia and Vascular Diseases | 1 year |
| Vascular Diseases (IIVD) | To study the prognosis of Intestinal (acute and chronic) Ischemia and Vascular Diseases | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Describe the prevalence of IIVD | 1 year | |
| Describe the prevalence of IIVD | 5 years | |
| Study mortality and its associated factors of IIVD |
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Inclusion Criteria:
Age > 18 years old
IMVI including :
acute mesenteric ischaemia defined by acute digestive distress in relation to arterial and/or venous, occlusive and/or non-occlusive splanchnic-mesenteric vascular insufficiency, in the absence of an alternative diagnosis
Exclusion Criteria:
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active patient file of the SURVI service
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Olivier CORCOS | Contact | 0140875000 | olivier.corcos@aphp.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Olivier CORCOS | Recruiting | Clichy | 92110 | France |
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| ID | Term |
|---|---|
| D065666 | Mesenteric Ischemia |
| ID | Term |
|---|---|
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010532 | Peritoneal Diseases |
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| 1 year |
| Study mortality and its associated factors of IIVD | 5 years |
| Study the risk of intestinal resection of IIVD and its associated factors. Among resected patients, describe the incidence of short intestinal syndrome and dependence on parenteral nutrition | 1 year |
| Study the risk of intestinal resection of IIVD and its associated factors. Among resected patients, describe the incidence of short intestinal syndrome and dependence on parenteral nutrition | 5 years |
| To study the risk of vascular restenosis in all revascularised patients with IIVD and its associated factors | 1 year |
| To study the risk of vascular restenosis in all revascularised patients with IIVD and its associated factors | 5 years |
| To study the incidence of recurrence or ischaemic complications (acute or chronic) in IIVD and their associated factors. | 1 year |
| To study the incidence of recurrence or ischaemic complications (acute or chronic) in IIVD and their associated factors. | 5 years |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |