Background of the study:

Hysterosalpingography (HSG) is widely used for the female infertility workup. Many studies have demonstrated that the use of oil-soluble contrast medium (OSCM) ethiodized oil for HSG surgery can improve pregnancy rates. However,The 24-hour delayed radiographs of OSCM HSG also brought some inconvenience to the patients , for example, patients need to make two trips to the hospital.

Objective of the study:

The purpose of this study was to compare OSCM HSGs using 4-hour and 24-hour delayed radiographs in terms of diagnosing tubal patency and identifying the presence of pelvic adhesions.

Study design:

Prospective, open label, self - controlled study

Study population:

Infertile patients scheduled for an OSCM HSG

Inclusion Criteria:

• Having spontaneous ovulation or inducing ovulation;
• Infertility lasting for 12 months;
• Conforms to the indications of hysterosalpingography;
• Understand and sign the informed consent;

Exclusion Criteria:

• Iodine allergy or hyperthyroidism
• Acute genital tract inflammation or abnormal leucorrhea examination;
• Abnormal vaginal bleeding;
• Fever or preoperative temperature higher than 37.5℃ within 3 days before angiography;
• Severe insufficiency of cardiopulmonary or liver function;
• During pregnancy and menstruation;
• With complications that may cause subjects to be unable to follow the study plan or even endanger the patient's safety or social environment;
• Patients who are participating in other clinical studies or who are not suitable for inclusion in this study due to other reasons considered by the researchers.