RSV Burden in Outpatient and Hospital Settings

Ambulatory Respiratory Tract Infection Survey, Burden of Respiratory Syncitial Virus in the Era of Covid-19

Strengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)

The study protocol is designed with three key components: 1. Build on existing PARI outpatient syndromic surveillance by adding laboratory multiplex testing of LRTI samples (RSV, Influenza, SARS-COV-2) 2. Follow all bronchiolitis through the PARI RWE database and document "patient journey" for 5 years after first medical visit 3. Review the electronic PARI data of three previous seasons in order to document the impact of LRTI attributable to RSV in children < 2 years in France prior to enhanced surveillance

Inclusion Criteria:

• children under 24 months of age (≤)
• One of the holders of parental authority signed the consent
• Patient affiliated to a social security scheme (Social Security or Universal Medical Coverage)
• Acute purulent otitis media (Paradise Criteria) or otorrhea with or withitout associated bronchiolitis

Exclusion Criteria:

• Age >24 months
• Refusal by one of the parents
• Not affiliated to a social security system
• Maternal RSV vaccination during the pregnancy of the included child