Individualizing tDCS Dose

Testing the Effects of Individualized and 4mA tDCS

Transcranial direct current stimulation (tDCS) is a noninvasive method of modulating brain activity and has therapeutic potential in many neurological and psychiatric conditions. However, unlike every current FDA-approved form of brain stimulation, there is no method of individualizing stimulation dose. In this study, a method of individualizing tDCS dose on behavioral outcomes and whether this could help to improve the consistency and magnitude of the stimulation effects will be tested.

Inclusion Criteria:

• Healthy volunteers or chronic stroke participants (at least 6 months prior to the study)
• No history of epilepsy
• No metal in the body
• No contraindications for TMS or MRI scanning
• Right handed
• Ability to find motor hotspot and acquire motor evoked potentials

Exclusion Criteria:

• Metal in the body
• History of epilepsy or claustrophobia
• Alcohol or substance abuse or dependence
• Current treatment for any psychiatric conditions (pharmacological or otherwise)
• Pregnant or actively breastfeeding