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The study is to examine the effect of functional trunk training on trunk control and upper extremity functions in patients with autosomal recessive ataxia.
Hereditary ataxias are a group of genetic diseases characterized by slow progressive gait disturbance. In addition, coordination disorders can be seen in extremities, speech and eye movements. Atrophy is common in the cerebellum. Friedreich's ataxia, ataxia telangiectasia, ataxia with vitamin E deficiency, infantile-onset spinocerebellar atrophy and Marinesco-Sjögren syndrome are autosomal recessive hereditary ataxias. The constant main sign of autosomal recessive ataxia is progressive ataxia.
The trunk has an important role on dynamic stabilization for postural reactions and limb movements. A good trunk support enables movements in other parts of the body to occur more regularly. Trunk stabilization is important to support upper and lower extremity movements, to meet the loads, and to protect the spinal cord. The relationship between upper extremity function, daily living activities and trunk functions has been emphasized in many studies but comparative studies about the rehabilitation were very less.
This study is to evaluate the effect o functional trunk training in patients with autosomal recessive ataxia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Active Comparator | Routine training; mat exercises and perturbation training |
|
| Study | Experimental | Trunk training; Functional training, mat exercises and perturbation training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Functional training | Other | The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The functional reach (forward-lateral-cross), trunk rotation exercises were performed in the sitting positions.(25min) Facilitation of trunk extension and elongation in the prone position (10 min). Thoracic mobilization on exercise ball (10min). |
| Measure | Description | Time Frame |
|---|---|---|
| The Functional Independence | The Functional Independence Scale for Children (WeeFIM) was used determine to independence level. | through of te study, average 8 weeks |
| Trunk impairment | The Trunk Disorder Scale (TIS) was used to assess static and dynamic sitting balance and trunk coordination | through of te study, average 8 weeks |
| The severity of ataxia | The International Ataxia Rating Scale (ICARS) was used to determine the severity | through of te study, average 8 weeks |
| The quality of life | The Children's Quality of Life Scale (PedsQL) was used determine to quality of life level. | through of te study, average 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Upper extremity functional performance | The 9-Hole Peg test was used to evaluate upper extremity performance | through of te study, average 8 weeks |
| Functional Reach Test | Functional Reach Test was used determine to dynamic trunk balance |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hasan kalyoncu üniversitesi | Gaziantep | Eyalet/Yerleşke | 27100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20649489 | Background | Freund JE, Stetts DM. Use of trunk stabilization and locomotor training in an adult with cerebellar ataxia: a single system design. Physiother Theory Pract. 2010 Oct;26(7):447-58. doi: 10.3109/09593980903532234. | |
| 15838852 | Background | Van de Warrenburg BP, Bakker M, Kremer BP, Bloem BR, Allum JH. Trunk sway in patients with spinocerebellar ataxia. Mov Disord. 2005 Aug;20(8):1006-13. doi: 10.1002/mds.20486. |
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| ID | Term |
|---|---|
| D020754 | Spinocerebellar Ataxias |
| D013132 | Spinocerebellar Degenerations |
| D001259 | Ataxia |
| ID | Term |
|---|---|
| D002524 | Cerebellar Ataxia |
| D002526 | Cerebellar Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Participants were divided in two groups. Two groups will get two different intervention.
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|
| Routine training | Other | The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The strengthening exercises were applied on the mat (3x10 for the first 4 weeks and 3x15 repetition for the last 4 weeks). Eyes open-closed perturbation training was performed for trunk control in sitting and standing positions (10 min.). |
|
| through of te study, average 8 weeks |
| 19823893 | Background | Corben LA, Tai G, Wilson C, Collins V, Churchyard AJ, Delatycki MB. A comparison of three measures of upper limb function in Friedreich ataxia. J Neurol. 2010 Apr;257(4):518-23. doi: 10.1007/s00415-009-5352-7. Epub 2009 Oct 13. |
| 27372366 | Background | Freund JE, Stetts DM, Vallabhajosula S. Relationships between trunk performance, gait and postural control in persons with multiple sclerosis. NeuroRehabilitation. 2016 Jun 30;39(2):305-17. doi: 10.3233/NRE-161362. |
| D009422 |
| Nervous System Diseases |
| D013118 | Spinal Cord Diseases |
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |