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This is a multi-site, non-randomized, data collection study. The purpose of this study is to investigate the cardiac electrical and mechanical function during LBBAP with different AV intervals.
Left bundle branch pacing (LBBP), achieved via trans-septal approach with the pacing tip at the left side of the ventricular septum, has recently initiated and been well practiced in China. LBBP is characterized with relatively ease of implantation (usually <5 minutes fluoroscopic use time), narrow paced QRS duration (similar to physiological pacing), low and stable pacing threshold (usually around 0.5V @0.5ms, good for device longevity and long-term stability without need of back-up pacing lead), high R wave amplitude for pacing management, and LBBB (left bundle branch block) correction by a low pacing output.
LBBAP (left bundle branch area pacing) can generate a relatively narrow QRSd and fast left ventricular activation. As AV interval is an important pacing parameter relevant to cardiac function. This study is to investigate the cardiac electrical and mechanical function during LBBAP with different AV intervals.
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| Measure | Description | Time Frame |
|---|---|---|
| ECG QRS duration | The primary endpoint is QRS duration during LBBP | At least 3 months post implant |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who received LBBAP for at least 3 months and come back to hospital for regular follow-up will be considered to be recruited voluntarily.
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| Name | Affiliation | Role |
|---|---|---|
| Xiaohong Zhou | Medtronic | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital | Beijing | Beijing Municipality | 100037 | China | ||
| Shanghai Chest Hospital |
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| Shanghai |
| Shanghai Municipality |
| 200030 |
| China |
| Zhejiang Greentown Cardiovascular Hospital | Hangzhou | Zhejiang | 310011 | China |
| Sir Run Run Shaw Hospital | Hangzhou | Zhejiang | 310020 | China |