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| Name | Class |
|---|---|
| Royal National Orthopaedic Hospital NHS Trust | OTHER |
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Observational case-control study to see if the Margin of Stability and Dynamic Postural Stability (measured using a motion capture gait laboratory and wearable device, respectively) are different in children with Adolescent Idiopathic Scoliosis and matched controls. Participants will walk across level ground and on a treadmill once for data collection and no follow-up is required.
The goal of this observational case-control study is to validate the Margin of Stability (MoS) and Dynamic Postural Stability (DPS) measures using a motion capture gait laboratory and wearable device in patients with Adolescent Idiopathic Scoliosis (AIS).
These measures will provide a consultant with objective data about a patient's movement and balance that the consultant and other healthcare professionals can use to infer about their spinal deformity progression or improvement. This research is an early step for working towards providing a distance medicine, non-invasive outcome measure that can be used alongside or in the absence of current clinical measures and radiography. Use of this data could reduce the frequency with which radiographs are required and so reduce the impact of radiation exposure. This wearable device could complement and improve upon existing outcome measures in the treatment of spinal deformity, reduce the need for radiographs and ameliorate the need for distance patient monitoring methods. A motion capture gait laboratory will be used as the gold-standard comparison.
A pilot study has been carried out on healthy participants with a simulated spinal deformity in a kinematic gait laboratory and using the wearable device, which showed altered balance in the simulated scoliosis group compared to controls.
The aim of this project is to:
Participants will attend one data collection appointment where they will walk across level ground and on a treadmill. No follow-up is required.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Case | Participants will attend one data collection appointment wearing form-fitting sports clothing and trainers. Participants will wear infrared markers and wearable devices whilst walking over level ground and on a treadmill. Data will be collected using a motion capture system and the wearable devices themselves. Data collection will take approximately 90 minutes |
| |
| Control | Participants will attend one data collection appointment wearing form-fitting sports clothing and trainers. Participants will wear infrared markers and wearable devices whilst walking over level ground and on a treadmill. Data will be collected using a motion capture system and the wearable devices themselves. Data collection will take approximately 90 minutes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gait analysis | Device | Collecting movement data whilst participants walk |
|
| Measure | Description | Time Frame |
|---|---|---|
| Margin of stability | Data collection appointment 1 - approx. 90 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Dynamic Postural Stability | Data collection appointment 1 - approx. 90 minutes | |
| Correlation between Margin of Stability and radiographic Cobb angle | Data collection appointment 1 - approx. 90 minutes |
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Case Inclusion Criteria:
Control Inclusion Criteria:
Case & Control Exclusion Criteria:
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Patient records will be accessed by a member of the clinical care team with legitimate access to patient records and who is independent to the research team to identify eligible patients as 'Case' participants. These patients and their parents will be approached with a letter asking them to contact the researcher if they are interested in participating. Additionally, recruitment posters will be displayed in the RNOH outpatient and RNOH orthotics departments.
For 'Control' participants, with permission from the participating schools and colleges, a letter will be sent to parents of children aged 10-18 at local schools and colleges requesting they volunteer for this study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fraye Watson | Contact | 07749350940 | fraye.watson.18@ucl.ac.uk | |
| Julian Leong | Contact | julian@leong.org.uk |
| Name | Affiliation | Role |
|---|---|---|
| Rui Loureiro | University College, London | Principal Investigator |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 25, 2026 |
| ID | Term |
|---|---|
| D000077107 | Gait Analysis |
| ID | Term |
|---|---|
| D005684 | Gait |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Correlation between Dynamic Postural Stability and radiographic Cobb angle | Data collection appointment 1 - approx. 90 minutes |
| D000076604 |
| Physical Functional Performance |
| D010809 | Physical Fitness |
| D006262 | Health |
| D011154 | Population Characteristics |