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The study is a cross sectional observational multicenter study. It is established in collaboration with the Egyptian college of rheumatology study group (ECRsg). It is conditioned that all the study participants had either mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal (MTP) joint in patients with a known history of gout or at high risk. Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjogren's syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis, seronegative spondyloarthropathy, will be excluded from the study. None of the participants had a history of intra-articular injection or aspiration in the scanned joints for 3 months prior to the inclusion in the study. The sonographers will be blinded for clinical data and the EULAR scanning protocol for the knee and 1st MTP will be considered [2]. Further, scanning of the double contour sign over the femur condyles anteriorly and posteriorly in sagittal planes will be assessed. All the sonographers in the study had an experience between 5 and 10 years in the field of musculoskeletal ultrasound.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sohag university recruited patients |
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| Minia university recruited patients |
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| Assuit university recruited patients |
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| Kasr Elini recruited patients |
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| Tanta university recruited patients |
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| Monofia university recruited patients |
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| Aswan university recruited patients |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Evaluation of sonographic signs of gouty arthritis | Diagnostic Test | the EULAR scanning protocol for the knee and 1st MTP will be considered [2]. Further, scanning of the double contour sign over the femur condyles anteriorly and posteriorly in sagittal planes will be assessed. Examination of erosions, tophus, double contour, effusion, and echogenic foci will be recorded. |
| Measure | Description | Time Frame |
|---|---|---|
| Sonographic signs of gouty arthritis in the knee or 1st MTP joint | Erosions, effusion, echogenic foci, and tophus using OMERACT definitions of sonographic signs of gouty arthritis | at baseline |
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Inclusion Criteria:
Exclusion Criteria:
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The study population will be collected from several university clinics all over Egypt. All are aged 40 or more with a history of definite gouty arthritis or at high risk and they have active arthritis of at least one joint.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed Elsaman | Sohag | Sohag Governorate | 82749 | Egypt |
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| Ain shams university recruited patients |
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