Strokes management, secondary to proximal arterial occlusion, by endovascular thrombectomy (TM) is now well established. The immuno-inflammatory events of reperfusion after TM are discussed. Systemic inflammation is a major factor suggested to explain the limited recovery of the ischemic parenchyma. Understanding these phenomena is necessary before developing an immunomodulatory strategy.

GROUP "AVC" :

Inclusion Criteria:

• Adults patient (s)
• Ischemic stroke by occlusion of a middle cerebral artery (proximal portion M1)
• Initial diagnostic MRI infusion
• TM with complete reperfusion (TICI 2b, 2c or 3)
• TM performed under local anesthesia +/- anxiolysis, or sedation including propofol
• mRS prior to stroke <2
• Barthel index <90
• Included in the HIBISCUS cohort
• Patient who was informed and did not object to participating in the study OR included through the emergency procedure then collection of his non-objection or that of his trusted person as soon as possible

Exclusion Criteria:

• NIHSS awareness score> or = 2
• Haemorrhagic complication before thrombectomy
• Pregnant woman
• Multiple vascular occlusions
• Occlusions of posterior or anterior cerebral territories other than M1
• Protected major
• TM performed under general anesthesia
• Other vital failure than neurological failure

GROUP "CONTROL" :

Inclusion Criteria:

• Adults patient (s)
• mRS <2
• Barthel index <90
• Requiring diagnostic arteriography for routine check-up of a cerebrovascular malformation
• Patient who was informed and did not object to participating in the study

Exclusion Criteria:

• NIHSS awareness score> or = 2
• Pregnant woman
• Protected major
• Exam performed under general anesthesia

Patients hospitalized for TM after a proximal ischemic stroke of the middle cerebral artery and whose reperfusion is satisfactory (TICI 2b, 2c and 3).

Population of control patients, consisting of patients admitted on an outpatient basis for diagnostic cerebral arteriography.