This is a prospective, national, randomized, multicenter, parallel group, Phase III study that evaluates the effects of AI201901 in Allergic Rhinitis patients, where they will spray twice a day against azelastine into both nostrils during a 28-day follow-up period.

Inclusion Criteria:

• To be diagnosed as allergic rhinitis on the basis of medical history, physical examination, and skin prick test, and according to ARIA 2008 criteria
• To be included in seasonal and perennial allergic rhinitis group
• To have a related complaint for at least 2 years
• To be informed about the study and to give consent to participate in the study

Exclusion Criteria:

• Diagnosis of superficial nasal mucosal erosion, moderate nasal mucosal erosion, nasal mucosal ulceration and nasal septum perforation during nasal examination
• Presence of nasal diseases that are likely to affect the accumulation of intranasal drugs, such as acute or chronic sinusitis, rhinitis medicamentosa, clinically significant polyposis or clinically significant nasal structural abnormalities
• Having undergone a nasal or sinus surgery for up to one year before the study
• The use of systemic or topical steroids within the last 15 days prior to inclusion in the study
• The use of antihistamine, chromoline Na within the last 15 days prior to inclusion in the study
• The use of any investigational drug within 30 days prior to Visit 1;
• Known hypersensitivity to components of the products used in the study
• Presence of respiratory infections, which have developed within the two weeks prior to Visit 1
• Diagnosis of COPD
• A history of alcohol or drug addiction treatment within the last 2 years prior to inclusion in the study, or any current addiction on alcohol or drugs,
• Use of alcohol and other drugs (antidepressants) that have a negative effect on reaction time / concurrent use of sedative drugs or other drugs that act on the central nervous system
• Presence of significant lung diseases including asthma. ((Only patients with intermittent asthma who need short-acting inhaled bronchodilators (no more than twice a week) and do not wake up at night due to asthma are suitable for inclusion)).
• Presence of chronic obstructive sleep-apnea syndrome (clinical diagnosis)
• Presence of any surgical or medical condition, which, according to the opinion of the responsible researcher, could significantly alter the absorption, distribution, metabolism, or excretion of the investigational product, or could significantly affect the patient's ability to complete this study
• Presence of symptoms in the medical history in relation to glaucoma, cataract, ocular herpes simplex, conjunctivitis, or other ocular infections
• Presence of medical history in relation to active or latent tuberculosis
• Presence or risk of exposure to chickenpox or measles within the last 30 days
• Presence of untreated fungi, bacteria or systemic viral infection within the last 30 days
• Being pregnant or breastfeeding
• Women of reproductive age who do not use a medically valid contraceptive method
• Presence of cystic fibrosis
• Presence of primary ciliary dyskinesia
• Use of intranasal or systemic first-generation antihistamines, leukotriene receptor antagonists or other nasal decongestants during the study
• Use of any ophthalmic steroid or nasal, inhaled or systemic steroid during the study
• Use of another clinical research product during the study