PREG - Offspring: Investigation of Children From Mothers With and Without Gestational Diabetes

PREG-Offspring: Untersuchung Von Kindern Von Teilnehmerinnen Der Deutschen Studie Gestationsdiabetes (PREG-Studie)

Gestational diabetes is the most common complication during pregrancy. With a screening between week 24 and 28 of gestation women with gestational diabetes can be identified and treated. Treatment comprises modification of diet and in some cases taking medication. This treatment lowers undesirable events like macrosomia or premature birth. However, unitl gestational diabetes is diagnosed the fetus is exposed to increased intrauterine glucose levels. The long-term effects of a well-managed gestational diabetes on the development of the offspring is still not well understood. Therefore, the PREG - Offspring study investigates several aspects of development in children from healthy and gestational diabetes mothers until adulthood.

Inclusion Criteria:

• signed informed consent provided by child and parent
• documented oral glucose tolerance test of the mother during pregnancy
• adequate management of gestational diabetes until birth

Exclusion Criteria:

• severe malformation that makes an examination impossible
• existent of coagulation disorder with increased risk of bleeding after blood sampling