Effects of Photobiomodulation on Changes in Cognitive Function and rCBF in MCI

Effects and Safety Evaluation of Changes in Cognitive Function of Photobiomodulation Treatment for Patients With Mild Cognitive Impairment (MCI): Single-institutional Prospective Clinical Trial, Single Group, Pilot Trial

This pilot study has two goals. The first is to see if the cognitive improves when VA and CA are stimulated in MCI patients, and the second is to do an explanatory data analysis to see if that improves cognitive in relation to the rCBF improvement.

After being informed about the study and potential risks, all patients giving written informed codsent sill undergo a 1 day screening period to determine eligibility for study entry. Subjects who pass the screening test will receive a registration number within 7 days and proceed with the pre-intervention test as follows.

Inclusion Criteria:

• The patients with mild cognitive impairment(MCI). The MCI was diagnosed based on medical history and neurological examination
• A sufficient level of education to understand study procedures and be able to communicate with site personnel

Exclusion Criteria:

• Any psychiatric disorders such as schizophrenia that would compromise participation
• Those with central nervous system disease
• Serious cognitive problems(MoCA score 7 or less).