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It is known that there is a complex relationship between tuberculosis and COPD. Post-tuberculosis airway disease or COPD associated with tuberculosis occurs in a significant portion of tuberculosis patients. However, it was observed that mortality rates and exacerbation rates of COPD patients with tuberculosis sequel were higher. However, the effect of tuberculosis sequela on functional outcomes in COPD patients has not been investigated in the studies.
The aim of this study is to determine whether the previous tuberculosis sequelae has a functional effect on patients with COPD.
This research is planned as a cross-sectional study. It will start within one week following the approval of the ethics committee and will be completed within one year. The universe of the study is S.B.Ü. Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital consists of patients who apply to Pulmonary Rehabilitation Outpatient Clinic. Participants will consist of two different groups: COPD patients with tuberculosis and COPD patients without tuberculosis. The voluntary principle will be taken into account in participating in the research.
Within the scope of the evaluation; Demographic and clinical information of the people who will participate in the study will be recorded, and Thorax CT and PFT examinations performed within the polyclinic service within the last 1 month will be evaluated. Saint George Respiratory Questionaire (SGRQ), 6-minute walk test (6MWT), Medical Research Council Dyspnea Scale (MRC), COPD assessment test (CAT) will be applied to the patients. Regarding the illness histories, the number of hospitalizations and emergency admissions in the last 1 year will be recorded. Detailed tuberculosis anamneses will also be taken from patients with tuberculosis sequelae.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COPD patients with tuberculous sequelae | COPD patients with tuberculous sequelae |
| |
| COPD patients without tuberculosis sequela | COPD patients with tuberculous sequelae |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Functional Outcome Measurements | Other | Dyspnea Exercise capacity Quality of life assessment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Exercise Capacity | Six minutes walk test | 6 minutes- baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Dyspnea Assessment | Medical Research Council Scale(MRC) | 5 minutes- baseline |
| COPD Assessment | COPD Assessment Test (CAT | 5 minutes- baseline |
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Inclusion Criteria:
Exclusion Criteria:
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COPD patients with tuberculous sequelae and COPD patients without tuberculosis sequela
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| İlknur N Gürşan, Assoc Prof | Contact | 05356954634 | ilknurnaz4@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Hulya Sahin | Izmir Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| İlknur Naz Gürşan | Recruiting | Izmir | 35620 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D014376 | Tuberculosis |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| Quality of Life Assessment | St. George Respiratory Questionaire | 20 minutes- baseline |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |