Effects of Insomnia Treatment on Metabolism in Patients With Depression

Effects of Insomnia Treatment on Metabolism in Patients With Depression

This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.

Inclusion Criteria:

• Insomnia Severity Index > 14
• Meet diagnostic criteria for Insomnia
• Meet diagnostic criteria for Major Depressive Disorder
• Either currently taking an SSRI/SNRI or no antidepressant

Exclusion Criteria:

• BMI > 30
• Those with unstable medical conditions defined by change in diagnosis or medication in past 2 months
• Those with clinically significant comorbid psychiatric conditions (e.g., Bipolar disorder)
• Those with known untreated sleep apnea or other clinically significant sleep disorder other than insomnia
• Those currently taking medications that affect sleep or metabolism (e.g., stimulants, thyroid meds)