With the Westernization of the diet and insufficient exercise, Taiwan's population of obesity, diabetes, and hyperlipidemia has increased in recent years, and the prevalence of the non-alcoholic fatty liver disease has gradually increased. Although weight loss, dietary adjustments, and certain drug treatments can delay the deterioration of the disease; however, weight loss and dietary adjustment are not easy.

With the Westernization of the diet and insufficient exercise, Taiwan's population of obesity, diabetes, and hyperlipidemia has increased in recent years, and the prevalence of the non-alcoholic fatty liver disease has gradually increased. Although weight loss, dietary adjustments, and certain drug treatments can delay the deterioration of the disease; however, weight loss and dietary adjustment are not easy. Moreover, drugs also have side effects, and there is currently no convenient and effective treatment for people who have non-alcoholic fatty liver disease. The purpose of this trial is that investigating and evaluating the effects on fatty liver, liver fiber, and metabolic indexes after subjects using Shen Pu Yang Gan Wan.

Inclusion Criteria:

• Patients with fatty liver diagnosed by abdominal ultrasound or hepatic fibrometer within half a year's data
• Subjects with the non-alcoholic fatty liver disease
• The severity of fatty liver should be at least 3 points by taking an abdominal ultrasound

Exclusion Criteria:

• Female patients are pregnant or breastfeeding.
• Patients with viral hepatitis.
• Long-term drinkers.
• Those who use slimming products and vitamin E.