Inclusion Criteria:
Groupe1:Ischemic embolic stroke of undetermined source (ESUS) according to TOAST criteria (N =10)
- Age ≥ 18 years old
- Non-gap ischemic stroke diagnosed on MRI or CT scan of the brain (gap stroke defined as a cerebral infarction ≤ 1.5 cm / ≤2.0 cm on diffusion sequences).
- No major cardio-embolic source (episode of atrial fibrillation or flutter > 6min, intracardiac thrombus, LVEF <30 percent recent myocardial infarction (<4 weeks), mitral stenosis, valvular vegetation or infectious endocarditis).
- Absence of atherosclerosis causing stenosis ≥ 50 percent of the lumen of the intra or extra cranial arteries that vascularise the infarcted cerebral area.
- No other specific cause identified (arteritis, arterial dissection, migraine/vaso-spasm, toxic cause).
- Affiliation to a social security scheme
- Patient who signed the consent
Group 2: Non-paroxysmal AF (N=10)
- Age ≥ 18 years old
- Subject with documented non-paroxysmal AF
- Affiliation to a social security scheme
- Patient who signed the consent
Group 3: Healthy volunteers (N=10)
Pre-inclusion criteria :
- Age ≥ 45 years old
- Patient with no documented cardiac or neuro-vascular history
- Affiliation to a social security scheme
- Patient who signed the consent
- Registration on the VRB file (Volontaires Recherches Biomédicales, https://vrb.sante.gouv.fr) or response to the published announcement
Criteria for inclusion :
- ECG in sinus rhythm
- Holter ECG: no AF
- Normal Trans thoracic echocardiography
- Patient with no neuro-vascular history
Group 4: Stroke-ESUS or non-paroxysmal AF with cardiac MRI (N=10)
- Age ≥ 18 years old
- Subject with a documented stroke-ESUS or documented non-paroxysmal FA
- Subject with cardiac MRI
- Affiliation to a social security scheme
- Subject having given its non-opposition
Exclusion Criteria:
Groupe1: Ischemic embolic stroke of undetermined source (ESUS) according to TOAST criteria (N =10)
- Risk of pregnancy or pregnancy (proven on interrogation data or pregnancy test).
- Contraindication to MRI ferromagnetic material (in particular pacemaker, implantable defibrillator, cardiac valve prosthesis, cochlear implant, neuro-stimulator, implanted automated injection material, intraocular metallic foreign body, neurosurgical and vascular clips, claustrophobia)
- Less than 8 weeks after implantation of a stent
- Subject participating in another intervention research including a period of exclusion still in progress at the pre-inclusion stage.
Group 2: Non-paroxysmal AF (N=10)
- Risk of pregnancy or pregnancy (proven on interview data or pregnancy test).
- Contraindication to MRI ferromagnetic material (in particular pacemaker, implantable defibrillators, cardiac valve prosthesis, cochlear implant, neurostimulators, implanted automated injection equipment, intraocular metallic foreign body, neurosurgical and vascular clips, claustrophobia).
- Less than 8 weeks after implantation of a stent
- Subject participating in another intervention research including a period of exclusion still in progress at the pre-inclusion stage.
Group 4: Stroke-ESUS or non paroxysmal AF with cardiac MRI (N=10)
- History of neuro-vascular or cardiac pathology
- Risk of pregnancy or pregnancy (proven on interrogation data or pregnancy test).
- Contraindication to MRI (ferromagnetic material (in particular pacemaker, implantable defibrillator, cardiac valve prosthesis, cochlear implant, neuro-stimulator, implanted automated injection material, intraocular metallic foreign body, neurosurgical and vascular clips, claustrophobia)
- Subject participating in another intervention research including a period of exclusion still in progress at the pre-inclusion stage.