Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Terminalia arjuna, commonly known as arjuna, that belongs to the family of Combretaceae. Most clinical and experimental studies for Terminalia arjuna, have suggested that the crude drug possesses anti-ischemic, antioxidant, hypolipidemic, and antiatherogenic activities.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oxyjun (Extract of Terminilia Arjuna). | Active Comparator |
| |
| Placebo (Microcrystalline cellulose) | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxyjun | Other | One capsule to be taken after breakfast with water. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Left ventricle ejection fraction | 1. To evaluate the effect of 8-week consumption of Oxyjun on cardiac pumping capacity of study participants as evaluated by Left ventricle ejection fraction (LVEF). | Day 0 to Day 56 |
| Measure | Description | Time Frame |
|---|---|---|
| Early filling (E) and the atrial phase (A) will be calculated at rest and the E/A ratio | Reduction in myocardial stress of study participants as evaluated by decrease in E/A ratio at the end of week 8 (day 56) from baseline as compared to placebo. | Day 0 to Day 56 |
| Myocardial stress |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Dr. Sanjay Wani, BAMS | Shop No.1,VardhmanApartment, Lokmanya Tilak Road,Dahisar west, Mumbai-400068. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dr. Awate clinic | Mumbai | Maharashtra | 400067 | India | ||
| Shree Polyclinic, |
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo | Other | One capsule to be taken after breakfast with water. |
|
Decline in myocardial stress of study participants as assessed by decrease in rate pressure product at the end of week 8 (day 56) from baseline (day 0) as compared to placebo. |
| Day 0 to Day 56 |
| Fatigue severity scale | Reduction in fatigue of study participants as assessed by decrease in Fatigue severity scale at week 4 (day 28), and week 8 (day 56) from baseline (day 0) as compared to placebo. | Day 0, Day 28, day 56 |
| Mumbai |
| Maharashtra |
| 400067 |
| India |
| Dr Rajesh Kewalramani Clinic | Mumbai | Maharashtra | 400068 | India |
| Dr. Wani's Clinic | Mumbai | Maharashtra | 400068 | India |