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Find out the deciding factor(total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) of neuromuscular blocker dose for deep neuromuscular blockade in bariatric surgery.
Before the surgery, total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index were measured by height and weight and skeletal muscle mass and body fat were measured by Bioelectrical impedance analysis (InbodyH20B). Find the highest correlation between the 8 factors (total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) and the amount of rocuronium administered to deep neuromuscular blockade in bariatric surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| obese patients | obese patients underwent bariatric surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| deep neuromuscular blockade in bariatric surgery | Drug | obese patients who underwent bariatric surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| the highest correlation coefficient | the relationship of rocuronium for deep neuromuscular blockade in bariatric surgery and 8 factors (corrected body weight, ideal body weight, lean body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) | preoperative 1 days to postoperative 1 days |
| Measure | Description | Time Frame |
|---|---|---|
| onset time of rocuronium | time from injection of rocuronium 0.6 mg/kg(TBW) to TOF ratio is less than 0.05 | preoperative 1 days to postoperative 1 days |
| time to deep neuromuscular blockade | time from injection of rocuronium 0.6 mg/kg(TBW) to PTC 1 |
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Inclusion Criteria:
Exclusion Criteria:
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obese patients who scheduled bariatric surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jiwon Han, Dr | Contact | 82-10-3447-1988 | hanjiwon@snubh.org | |
| Ah-young Oh, professor | Contact | 82-31-787-7506 | ohahyoung@hanmail.net |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30719949 | Background | Choi YJ, Hee Kim Y, Bae GE, Yu JH, Yoon SZ, Kang HW, Lee KS, Kim JH, Lee YS. Relationship between the muscle relaxation effect and body muscle mass measured using bioelectrical impedance analysis: A nonrandomized controlled trial. J Int Med Res. 2019 Apr;47(4):1521-1532. doi: 10.1177/0300060518822197. Epub 2019 Feb 5. |
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| ID | Term |
|---|---|
| D050110 | Bariatric Surgery |
| ID | Term |
|---|---|
| D049088 | Bariatrics |
| D000073319 | Obesity Management |
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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| preoperative 1 days to postoperative 1 days |
| Recovery time | time from sugammadex injection to TOF ratio > 0.9 | preoperative 1 days to postoperative 1 days |