Complex Peri-operative Intervention in Older Patients With Cancer

Implementation of coMplex PeRi-OperatiVe intervEntion in olDer Patients With Cancer : a Multicenter Randomized Controlled Trial

Incidence of digestive cancers increase and half of new cases will be people of 75 years or more in 2050. Surgery is one of the main treatment's strategy but post-operative morbi-mortality increases with age. Pre-operative Geriatric Assessment enable to identify frail or vulnerable patients at risk of post-operative complications.

The coordinating team postulate that a geriatric and surgical co-management with a combination of several targeted geriatric interventions with usual post-operative care could improve the post-operative care and decrease the risk of morbi-mortality in older patients with digestive cancers.

Multicenter Randomized Clinical Trial in 2 parallel-groups with masked adjudication of main endpoint

Inclusion Criteria:

• Aged 75 years or more
• Gastric, colo-rectal, pancreatic cancer or hepatic metastasis needed a surgical treatment
• Health Insurance
• At risk of post-operative complication through Surgical Risk Calculator (>25%) or surgeon judgment.
• Written consent

Exclusion Criteria:

• Surgery in emergency