The aim of this research is to evaluate autophagy markers in patients with endometrial polyps

Endometrial polyp are benign formations that are frequently encountered in gynecology practice and have malignant potential. It may be asymptomatic in the clinic or may present with abnormal uterine bleeding. Although its pathophysiology has not been clearly revealed, there are many studies in the literature about it. However, the autophagy pathway emerges as a subject that has never been evaluated. In this study, the investigators would like to prospectively evaluate Beclin 1, LC3A / B and p62 markers in the autophagy pathway in endometrial polyp tissue samples by immunohistochemistry and reveal their importance.

Inclusion Criteria:

• Patients over 35 years of age with a histopathologically confirmed diagnosis of endometrial polyp
• patients over the age of 35 whose histopathologically reported normal endometrial biopsy results.

Exclusion Criteria:

• Are under the age of 35,
• those with cognitive dysfunction,
• diagnosed with any type of cancer
• who are under treatment for cancer,
• diabetes mellitus,
• hypertension,
• endometriosis,
• adenomyosis,
• chronic endometritis,
• have an acute or chronic illness,
• patients who have smoked and used alcohol in the last 10 years

endometrial polyp

Patients with histopathologically proven endometrial polyp and healthy controls

When we conducted the study, we will plan to make individual participant data (IPD) available to other researchers.