The Effects of n-3 LCPUFAs in Patients With Colorectal Cancer

Single-blinded, Randomized, Controlled Trial About the Effects of n-3 LCPUFAs on Weight and Functional Status in Patients With Colorectal Cancer.

The aim of this study is to determine the effects of n-3 PUFAs on weight, physical funktion and quality of life in patients with colorectal cancer.

Primary outcomes:

• Weight
• Physical function
• Hand-grip strength

Secondary outcomes:

• Quality of life
• Mid-upperarm circumference
• Incorporation of n-3 PUFAs into cell membranes

Inclusion Criteria:

• ≥18 years
• Patients with diagnosed colorectal cancer with metastases treated with chemotherapy on Rigshospitalet, Copenhagen

Exclusion Criteria:

• < 18 years
• Patients in palliative care
• patients with haemophilia
• Patiens in treatment of anti-coagulation
• Patients with genetic hyperkolesterolemia
• Pre-dialytic patients (GFR<15ml/min/1,73m2 eller kreatinin ≥500 mmol/L)