Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 1810108 | Other Grant/Funding Number | Région Wallonne - Economié Emploi Recherche - Win2Wal |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Cliniques universitaires Saint-Luc- Université Catholique de Louvain | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
After a stroke, individuals present with motor and/or cognitive impairments. These impairments limit activity, restrict participation and affect quality of life. Therefore, rehabilitation programs are provided from the earliest days. However, an important proportion of patients do not achieve the recommended amount of rehabilitation therapy (even in institutional systems). In fact, patients do not always have access to healthcare systems. Moreover, hospital resources and healthcare systems are often limited (especially in poor countries) which has led to the development of new cost-effective rehabilitation methods such as self-rehabilitation and tele-rehabilitation.
This study aims :
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stroke patients | Experimental | Stroke patients with hemiparesis and/or cognitive impairments (such as apraxia, aphasia and hemineglect) |
|
| Healthy subjects | Experimental | Subjects who do not suffer from any pathology that could affect upper-limb motor function or cognition |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Motor and cognitive virtual reality-based assessments | Behavioral | Motor and cognitive testing in virtual reality |
|
| Measure | Description | Time Frame |
|---|---|---|
| Upper Extremity Fugl-Meyer Assessment | Highly recommended scale that assess upper limb motor function (0% = worse outcome; 100% best outcome). | Through study completion, on average 24 weeks |
| Box and Block Test | A measure of manual dexterity and activity that requires repeatedly moving 1-inch blocks from one side of a box to another in 60 seconds. | Through study completion, on average 24 weeks |
| The Bells Test | A cancellation task, permits a quantitative and qualitative evaluation of visual neglect | Through study completion, on average 24 weeks |
| Action Research Arm Test | A 19 item observational measure used by physical therapists and other health care professionals to assess upper extremity performance (coordination, dexterity and functioning). Items are categorized into four subscales (grasp, grip, pinch and gross movement) and arranged in order of decreasing difficulty, with the most difficult task examined first, followed by the least difficult task. Task performance is rated on a 4-point scale, ranging from 0 (no movement) to 3 (movement performed normally). | Through study completion, on average 24 weeks |
| System Usability Scale | Reliable tool for measuring the usability. It consists of a 10 item questionnaire with five response options for respondents; from Strongly agree to Strongly disagree | Through study completion, on average 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Upper limb 3D position | Upper limb 3D position will be measured with different virtual reality devices (Oculus Quest, htc Vive, REAtouch). This will be done thanks to the headset's infra-red camera or the controller's inertial measurement units. | Through study completion, on average 24 weeks |
| Upper limb peak velocity |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Gauthier Everard, MSc, PT | Contact | +32472500158 | gauthier.everard@uclouvain.be | |
| Khawla Ajana, MSc | Contact | khawla.ajana@uclouvain.be |
| Name | Affiliation | Role |
|---|---|---|
| Thierry Lejeune, MD, PhD | Cliniques universitaires Saint-Luc - UCLouvain | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cliniques universitaires Saint-Luc | Recruiting | Brussels | Woluwé | 1200 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41408291 | Derived | Sorrentino G, Edwards MG, Baldini N, Mustile M, Lejeune T, Everard G. REAsmash-ET: a methodological framework for combined cognitive and motor assessment through eye-tracking and kinematic metrics in immersive VR search-and-reach task. J Neuroeng Rehabil. 2025 Dec 17;23(1):25. doi: 10.1186/s12984-025-01844-0. | |
| 40053708 | Derived |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Studies will be conducted in a single group of (a) stroke patients and (b) healthy subjects
Not provided
Not provided
Not provided
Not provided
| Motor and cognitive virtual reality-based serious games | Behavioral | Serious games implemented in virtual reality to rehabilitate motor and cognitive impairments. |
|
Upper limb peak velocity will be measured with different virtual reality devices (Oculus Quest, htc Vive, REAtouch). This will be done by deriving 3D position (obtained previously thanks to the headset's infra-red camera or the controller's inertial measurement units) and extracting highest value. |
| Through study completion, on average 24 weeks |
| Upper limb smoothness | Upper limb smoothness will be measured with different virtual reality devices (Oculus Quest, htc Vive, REAtouch). This will be done by deriving three times 3D position (obtained previously thanks to the headset's infra-red camera or the controller's inertial measurement units) and converting it to a logarithmic dimensionless jerk. Second option is to measure a spectral arc length (also computed from 3D position) | Through study completion, on average 24 weeks |
| Everard G, Declerck L, Lejeune T, Edwards MG, Bogacki J, Reiprich C, Delvigne K, Legrain N, Batcho CS. A Self-Adaptive Serious Game to Improve Motor Learning Among Older Adults in Immersive Virtual Reality: Short-Term Longitudinal Pre-Post Study on Retention and Transfer. JMIR Aging. 2025 Mar 3;8:e64004. doi: 10.2196/64004. |
| 39973878 | Derived | Ajana K, Everard G, Lejeune T, Edwards MG. An immersive virtual reality serious game set for the clinical assessment of spatial attention impairments: Effects of avatars on perspective? Technol Health Care. 2025 Jul;33(4):1626-1644. doi: 10.1177/09287329241296380. Epub 2025 Jan 17. |
| 38491540 | Derived | Everard G, Burton Q, Van de Sype V, Bibentyo TN, Auvinet E, Edwards MG, Batcho CS, Lejeune T. Extended reality to assess post-stroke manual dexterity: contrasts between the classic box and block test, immersive virtual reality with controllers, with hand-tracking, and mixed-reality tests. J Neuroeng Rehabil. 2024 Mar 15;21(1):36. doi: 10.1186/s12984-024-01332-x. |
| 36463219 | Derived | Burton Q, Lejeune T, Dehem S, Lebrun N, Ajana K, Edwards MG, Everard G. Performing a shortened version of the Action Research Arm Test in immersive virtual reality to assess post-stroke upper limb activity. J Neuroeng Rehabil. 2022 Dec 3;19(1):133. doi: 10.1186/s12984-022-01114-3. |
| 35065678 | Derived | Everard G, Otmane-Tolba Y, Rosselli Z, Pellissier T, Ajana K, Dehem S, Auvinet E, Edwards MG, Lebleu J, Lejeune T. Concurrent validity of an immersive virtual reality version of the Box and Block Test to assess manual dexterity among patients with stroke. J Neuroeng Rehabil. 2022 Jan 22;19(1):7. doi: 10.1186/s12984-022-00981-0. |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D010291 | Paresis |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided