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ClinicalTrials.gov ID

NCT04694430

Lead Sponsor

Shenzhen People's HospitalOTHER

Overall Status

Unknown status

Study Type

Observational

Enrollment

500Estimated

Last Update Posted

Jan 5, 2021Actual

Start Date

Jan 1, 2021Estimated

Primary Completion Date

Jun 30, 2021Estimated

Completion Date

Dec 31, 2021Estimated

Official Title

A Integration of Respiratory Medicine and Prevention Multi-center Study to Determine the Prevalence and Influence of Pertussis on Chronic Obstructive Pulmonary Disease Exacerbation in Shenzhen by National Respiratory Diseases Clinical Medicine Research Center

Brief Summary

A prospective, multi-center, observational clinical trail. Aim to evaluate the real incidence of chronic obstructive pulmonary disease (COPD) pertussis and the impact of pertussis on COPD exacerbation.

Detailed Description

1. Investigate the incidence and epidemiological characteristics of pertussis infection in COPD population.
2. To explore the relationship between pertussis infection and COPD exacerbation.

• COPD Exacerbation
• Pertussis

• Blood sample
• Data collection
• Throat swab

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

- Clinical diagnosis of acute COPD

Exclusion Criteria:

- Major diseases except COPD; Significant abnormality in laboratory examination; Clinical diagnosis of lung cancer, bronchiectasis, pneumoconiosis or other simple restrictive ventilation dysfunction; Patients with a history of asthma, allergic rhinitis, or a blood eosinophil count of 2600/mm3 (0.6x10^9/L) within 4 weeks; Currently suffering from active tuberculosis; Patients with life-threatening pulmonary embolism, or al-antitrypsin deficiency, or cystic fibrosis; Patients who have undergone lung resection.

Observational Model

Case-Only

Time Perspective

Cross-Sectional

Lead Sponsor

Shenzhen People's HospitalOTHER

15914030269

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