Sedation Techniques for Outpatient Colonoscopy

Propofol Patient-controlled Sedation Versus Target-controlled Infusion in Outpatient Colonoscopy

This was a prospective, randomized, single-blind controlled clinical trial comparing three sedative regimens for outpatient colonoscopy.

This was a prospective, randomized, single-blind controlled clinical trial comparing target-controlled infusion (TCI) with propofol and patient-controlled sedation (PCS) with propofol, to conventional combination of midazolam and pethidine, in terms of quality and safety of sedation, and patient recovery during outpatient colonoscopy.

Inclusion Criteria:

• ASA I or II patients
• aged between 18 to 80 years
• scheduled for outpatient colonoscopy

Exclusion Criteria:

• history of or with psychiatric disease
• on psychoactive drugs
• mentally or physically unable to use the hand-held device for PCS
• previous complications from anaesthesia or sedation
• potentially difficult airway maintenance
• obstructive sleep apnoea
• pregnant
• with contraindications to the study drugs