Superficial Cryotherapy Versus Microneedling in Alopecia Areata

Comparative Study Between the Effect of Superficial Cryotherapy Using Dimethyl Ether and Propane Mixture and Microneedling in Treatment of Alopecia Areata

This study is randomized comparative analytical prospective study that included patients with mild and moderate alopecia areata. Patients was divided into two groups Patients in the first group underwent Superficial cryotherapy using dimethyl ether and propane (DMEP) at -57C (Cryotherapy group). Patients in the second group underwent Microneedling (Microneedling group). A total of six sessions were done at 2 weeks interval. Patients were followed-up for next 3 months to evaluate the persistence of hair regrowth after therapy. Patients were assessed at baseline and during follow up using photography, Dermoscopy, SALT score and regrowth scale.

Inclusion Criteria:

• ِAlopecia areata patients

Exclusion Criteria:

• Alopecia totalis and universalis
• ِAge less than four years.
• ِPregnancy or breast-feeding.
• ِActive infection at the site alopecia patch(s).
• ِInflammation ate site of the alopecia patches
• ِIntolerance to cold.
• ِAssociated systemic illness such as thyroid, pernicious anaemia, diabetes mellitus, autoimmune connective tissue diseases.
• ِPrevious treatment for alopecia areata over the last three months.