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The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy.
The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy. The intervention is systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).
Follow up after one month and three months by recording visual acuity and electro physiological studies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Systemic erythropoietin injections | Experimental | The study included 10 patients diagnosed as post papilledemic optic atrophy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Systemic erythropoietin injection | Drug | Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual acuity | VIsual acuity assessed at the follow up | 3 months |
| Pattern visual evoked Potential . | Pattern visual evoked Potential .in both eyes to use data of the normal fellow eye as patients' internal control | 3 months |
| Pattern electroretinogram | Pattern electroretinogram in both eyes to use data of the normal fellow eye as patients' internal control | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mai ElBahwash, PhD | Alexandria Faculty of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alexandria Faculty of Medicine | Alexandria | Egypt |
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| ID | Term |
|---|---|
| D009896 | Optic Atrophy |
| ID | Term |
|---|---|
| D009901 | Optic Nerve Diseases |
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |
| D005128 | Eye Diseases |
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The study included 10 patients diagnosed as post papilledemic optic atrophy that were attending Alexandria main university hospital. All patients underwent initially assessment of visual acuity, color vision, pupil reaction ,funduscopy and electrophysiological tests ( pattern visual evoked potential and pattern electroretinogram in both eyes to use data of the normal fellow eye as patients' internal control). Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days). Follow up after one month and three months by recording visual acuity and electro physiological studies.
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