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This study aims to evaluate whether the colorectal bundle designed and implemented at Cantonal Hospital Lucerne, will lead to a significant reduction of SSIs. The impact of potential risk factors for SSIs will additionally be evaluated.
Surgical site infections (SSIs) remain a relevant problem in colorectal surgery. The aim of this study is to implement a bundle of care in order to reduce SSIs in colorectal surgery.
All patients undergoing colorectal surgery between October 2018 and September 2021 will be included in a prospective observational study. Since our colorectal bundle has been established gradually, patients will be grouped in a pre-implementation (2018-2019), implementation (2019-2020) and post implementation phase (2020-2021), in order to assess the effectiveness of the actions undertaken. Primary endpoint of this study will be surgical site infection (SSI) rate, while secondary endpoints encompass potential risk factors for SSIs. We assume that obesity, age, diabetes, alcoholism and smoking may lead to a higher risk for SSIs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-implementation phase (October 2018 - September 2019) | During this time period, 137 patients underwent colorectal surgery. Only basic measures for preventing SSI were performed:
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| Implementation phase (October 2019 - September 2020) | During this phase, additional measures have been introduced:
| ||
| Post-implementation phase (October 2020 - September 2021) | During this phase, additional measures are implemented.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bundle of Care | Behavioral | Hair removal with Clipper Glucose Control Preoperative antibiotics Repeat antibiotics after 4 Hours Optimize Body temperature Instrument change for colorectal anastomosis Use of wound protectors Experienced surgeon Preoperative showering |
| Measure | Description | Time Frame |
|---|---|---|
| Surgical Site infection | rate of SSIs and classification of SSIs (superficial SSI, deep SSI or organ space SSI) | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Risk factors for SSI | Determination of the risk factors for SSI (Obesity, age, diabetes, alcoholism, immune-deficit illnesses (such as HIV and Hepatitis), smoking, immunosuppressive drugs, chemotherapy, radiotherapy, COPD, pAVK, renal insufficiency and poor Nutrition) | at surgery |
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Inclusion Criteria:
over 18 elective or emergency colorectal surgery written informed consent
Exclusion Criteria:
pregnant no informed consent
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Patients undergoing colorectal surgery in the Cantonal Hospital of Lucerne October 2020-September 2021
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jörn-Markus Gass | Contact | 0041412854835 | markus.gass@luks.ch |
| Name | Affiliation | Role |
|---|---|---|
| Jörn-Markus Gass | Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cantonal Hospital of Lucerne | Recruiting | Lucerne | 6000 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34616960 | Derived | Brunner S, Liesenberg J, Fourie L, Metzger J, Scheiwiller A, Zschokke I, Lehnick D, Gass JM. Implementation of a Bundle of Care in Colorectal Surgery to Reduce Surgical Site Infections Successfully at Cantonal Hospital Lucerne: Study Protocol for a Prospective Observational Study. Int J Surg Protoc. 2021 Sep 23;25(1):220-226. doi: 10.29337/ijsp.150. eCollection 2021. |
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| ID | Term |
|---|---|
| D013530 | Surgical Wound Infection |
| ID | Term |
|---|---|
| D014946 | Wound Infection |
| D007239 | Infections |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |