2 pills/day (1 pill every morning and 1 pill every evening) for 14 days

A battery of questionnaires is intended to understand key aspects of pain, mood, and function as quickly and efficiently as possible. The focus of these measures is on obtaining an accurate assessment of pain, while also asking about physical function, anxiety, and other associated somatic disturbances. These questionnaires will be taken prior to SCS implant (Baseline) and after SCS implant (1 week post-op, 4 weeks post-op, and 8 weeks post-op ) to assess and compare.

Neuropathic Pain Descriptors: The Pain DETECT is a 9-item measure of sensory descriptors and spatial and temporal characteristics that has demonstrated utility in identifying central neuropathic pain.

A battery of questionnaires is intended to understand key aspects of pain, mood, and function as quickly and efficiently as possible. The focus of these measures is on obtaining an accurate assessment of pain, while also asking about physical function, anxiety, and other associated somatic disturbances. These questionnaires will be taken prior to SCS implant (Baseline) and after SCS implant (1 week post-op, 4 weeks post-op, and 8 weeks post-op ) to assess and compare.

Neuropathic Pain Descriptors: The Pain DETECT is a 9-item measure of sensory descriptors and spatial and temporal characteristics that has demonstrated utility in identifying central neuropathic pain.

Catecholamines( Norepinephrine) Blood Test: pg/mL

• normal range for norepinephrine is 70 to 1700 pg/mL

Tumor necrosis factor-alpha (TNF-α) and interlukin-6 (IL6) Blood Test: pg/mL

• IL-6 normal values was 6-31 pg/mL
• TNF-α 5 pg/mL,

Lipid panel Blood Test: mg/dL,

• Total Cholesterol Less than 170mg/dL
• Non-HDL Less than 120mg/dL
• LDL Less than 100mg/dL
• HDL More than 45mg/dL

Metabolic Panel Blood Test (Electrolyte Check): mg/dL, mmol/L , g/dL, U/L, mEq/L

• Albumin: 3.4 to 5.4 g/dL (34 to 54 g/L)
• Alkaline phosphatase: 20 to 130 U/L
• ALT (alanine aminotransferase): 4 to 36 U/L
• AST (aspartate aminotransferase): 8 to 33 U/L
• BUN (blood urea nitrogen): 6 to 20 mg/dL (2.14 to 7.14 mmol/L)
• Calcium: 8.5 to 10.2 mg/dL (2.13 to 2.55 mmol/L)
• Chloride: 96 to 106 mEq/L (96 to 106 mmol/L)
• CO2 (carbon dioxide): 23 to 29 mEq/L (23 to 29 mmol/L)
• Creatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L)
• Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L)
• Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L)
• Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)
• Total bilirubin: 0.1 to 1.2 mg/dL (2 to 21 µmol/L)
• Total protein: 6.0 to 8.3 g/dL (60 to 83 g/L)

Stored plasma for inflammatory markers

Metabolic Panel Blood Test (Electrolyte Check): mg/dL, mmol/L , g/dL, U/L, mEq/L

• Albumin: 3.4 to 5.4 g/dL (34 to 54 g/L)
• Alkaline phosphatase: 20 to 130 U/L
• ALT (alanine aminotransferase): 4 to 36 U/L
• AST (aspartate aminotransferase): 8 to 33 U/L
• BUN (blood urea nitrogen): 6 to 20 mg/dL (2.14 to 7.14 mmol/L)
• Calcium: 8.5 to 10.2 mg/dL (2.13 to 2.55 mmol/L)
• Chloride: 96 to 106 mEq/L (96 to 106 mmol/L)
• CO2 (carbon dioxide): 23 to 29 mEq/L (23 to 29 mmol/L)
• Creatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L)
• Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L)
• Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L)
• Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)
• Total bilirubin: 0.1 to 1.2 mg/dL (2 to 21 µmol/L)
• Total protein: 6.0 to 8.3 g/dL (60 to 83 g/L)

Metabolic Panel Blood Test (Electrolyte Check): mg/dL, mmol/L , g/dL, U/L, mEq/L

• Albumin: 3.4 to 5.4 g/dL (34 to 54 g/L)
• Alkaline phosphatase: 20 to 130 U/L
• ALT (alanine aminotransferase): 4 to 36 U/L
• AST (aspartate aminotransferase): 8 to 33 U/L
• BUN (blood urea nitrogen): 6 to 20 mg/dL (2.14 to 7.14 mmol/L)
• Calcium: 8.5 to 10.2 mg/dL (2.13 to 2.55 mmol/L)
• Chloride: 96 to 106 mEq/L (96 to 106 mmol/L)
• CO2 (carbon dioxide): 23 to 29 mEq/L (23 to 29 mmol/L)
• Creatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L)
• Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L)
• Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L)
• Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)
• Total bilirubin: 0.1 to 1.2 mg/dL (2 to 21 µmol/L)
• Total protein: 6.0 to 8.3 g/dL (60 to 83 g/L)

Metabolic Panel Blood Test (Electrolyte Check): mg/dL, mmol/L , g/dL, U/L, mEq/L

• Albumin: 3.4 to 5.4 g/dL (34 to 54 g/L)
• Alkaline phosphatase: 20 to 130 U/L
• ALT (alanine aminotransferase): 4 to 36 U/L
• AST (aspartate aminotransferase): 8 to 33 U/L
• BUN (blood urea nitrogen): 6 to 20 mg/dL (2.14 to 7.14 mmol/L)
• Calcium: 8.5 to 10.2 mg/dL (2.13 to 2.55 mmol/L)
• Chloride: 96 to 106 mEq/L (96 to 106 mmol/L)
• CO2 (carbon dioxide): 23 to 29 mEq/L (23 to 29 mmol/L)
• Creatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L)
• Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L)
• Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L)
• Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)
• Total bilirubin: 0.1 to 1.2 mg/dL (2 to 21 µmol/L)
• Total protein: 6.0 to 8.3 g/dL (60 to 83 g/L)

Metabolic Panel Blood Test (Electrolyte Check): mg/dL, mmol/L , g/dL, U/L, mEq/L

• Albumin: 3.4 to 5.4 g/dL (34 to 54 g/L)
• Alkaline phosphatase: 20 to 130 U/L
• ALT (alanine aminotransferase): 4 to 36 U/L
• AST (aspartate aminotransferase): 8 to 33 U/L
• BUN (blood urea nitrogen): 6 to 20 mg/dL (2.14 to 7.14 mmol/L)
• Calcium: 8.5 to 10.2 mg/dL (2.13 to 2.55 mmol/L)
• Chloride: 96 to 106 mEq/L (96 to 106 mmol/L)
• CO2 (carbon dioxide): 23 to 29 mEq/L (23 to 29 mmol/L)
• Creatinine: 0.6 to 1.3 mg/dL (53 to 114.9 µmol/L)
• Glucose: 70 to 100 mg/dL (3.9 to 5.6 mmol/L)
• Potassium: 3.7 to 5.2 mEq/L (3.70 to 5.20 mmol/L)
• Sodium: 135 to 145 mEq/L (135 to 145 mmol/L)
• Total bilirubin: 0.1 to 1.2 mg/dL (2 to 21 µmol/L)
• Total protein: 6.0 to 8.3 g/dL (60 to 83 g/L)

Lipid panel Blood Test: mg/dL,

• Total Cholesterol Less than 170mg/dL
• Non-HDL Less than 120mg/dL
• LDL Less than 100mg/dL
• HDL More than 45mg/dL

Stored plasma for inflammatory markers Blood Test

Catecholamines( Norepinephrine) Blood Test: pg/mL

• normal range for norepinephrine is 70 to 1700 pg/mL

Tumor necrosis factor-alpha (TNF-α) and interlukin-6 (IL6) Blood Test: pg/mL

• IL-6 normal values was 6-31 pg/mL
• TNF-α 5 pg/mL,