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The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting, better surgical satisfaction and shortened the duration of surgery and anesthesia.
Keeping patients in normovolemic state and hemodynamically stable in anesthesia and intensive care practice are important goals of anesthesiologist. It is known that hypotension that develops after taking patients to the beach chair position has a negative effect on cerebral oxygenation. Aggressive fluid regimes using to prevent hypotension can cause glycocalyx damage, edema and organ dysfunction. Also hypertension seconday to vasopressor therapy can cause bleeding at the surgical site and impaired surgical visualization during the arthroscopic shoulder surgery.
In the literature, there are studies examine whether the hypotension is the result of decreased cardiac output or decreased systemic resistance and what should be the optimal treatment , but as far as investigators know, there is no study about effects of preloading before the beach chair position on hemodynamic parameters.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study group (preloading with crystalloid fluid - isotonic solution) | Experimental | Preloading with crystalloid fluid (isotonic solution) at 10 ml/kg of ideal body weight |
|
| Control group (not preloading) | No Intervention | no preloading |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Preloading with crystalloid fluid | Drug | crystalloid fluid at 10 ml/kg of ideal body weight was administered intravenously in 30 min before the BCP for patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean arterial pressure | (mmHg) | during surgery (spesicific time intervals (after induction - after BCP position - 0th min - 5th min - 10th min- 30th min- 60th min) |
| Cardiac output | (L/min) | during surgery (spesicific time intervals (after induction - after BCP position - 0th min - 5th min - 10th min- 30th min- 60th min) |
| Stroke volume variation | (%) data obtained from arterial contour analysis | during surgery (spesicific time intervals (after induction - after BCP position - 0th min - 5th min - 10th min- 30th min- 60th min) |
| Heart rate | bpm | during surgery (spesicific time intervals (after induction - after BCP position - 0th min - 5th min - 10th min- 30th min- 60th min) |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative nausea and vomiting | PONV rates | in postoperative first day |
| Surgical satisfaction rate | Surgical satisfaction scale (0-10, 0 lowest score, 10 highest score) (score) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Huru Ceren Gokduman, MD | Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology | Principal Investigator |
| Elif Aygun, MD | Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology | Study Chair |
| Nur Canbolat, MD | Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology | Principal Investigator |
| Mert Canbaz, MD | Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology | Study Director |
| Ali Ersen, MD | Istanbul Unıversity, Istanbul Faculty of Medicine Traumatology and Orthopedics | Study Chair |
| Mehmet Buget, MD | Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul Unıversity, Istanbul Faculty of Medicine | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24904427 | Background | Larsen SL, Lyngeraa TS, Maschmann CP, Van Lieshout JJ, Pott FC. Cardiovascular consequence of reclining vs. sitting beach-chair body position for induction of anesthesia. Front Physiol. 2014 May 19;5:187. doi: 10.3389/fphys.2014.00187. eCollection 2014. | |
| 22290457 | Background | Woodcock TE, Woodcock TM. Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy. Br J Anaesth. 2012 Mar;108(3):384-94. doi: 10.1093/bja/aer515. Epub 2012 Jan 29. |
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| ID | Term |
|---|---|
| D000070599 | Shoulder Injuries |
| D020250 | Postoperative Nausea and Vomiting |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Study group - Control group
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Single-blind
| in postoperative first day |
| The duration of anesthesia and surgery | The duration of anesthesia and surgery (min) | during surgery |
| Ephedrine usage | total ephedrine dose (mg) used during surgery | during surgery |
| Total amount of crystalloid and colloid | Total amount of crystalloid and colloid (ml) | during surgery |
| 24472443 | Background | Chamos C, Vele L, Hamilton M, Cecconi M. Less invasive methods of advanced hemodynamic monitoring: principles, devices, and their role in the perioperative hemodynamic optimization. Perioper Med (Lond). 2013 Sep 17;2(1):19. doi: 10.1186/2047-0525-2-19. |
| D009325 | Nausea |
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D014839 | Vomiting |