Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 283766 | Other Identifier | IRAS |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| DermBiont, Inc. | INDUSTRY |
| University College London Hospitals | OTHER |
| The Whittington Hospital NHS Trust | OTHER_GOV |
Not provided
Not provided
Not provided
Not provided
An observational study of patients with COVID-19 confirmed cases (with various degrees of severity) and controls.
Oral and nasal swabs will be taken from 150 patients (50 with mild form and 50 with severe form of COVID-19 with or without mechanical ventilation, 50 healthy controls).
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Controls tested PCR (-) for COVID-19 |
| ||
| Tested PCR (+) for COVID-19, Mild - not admitted to the hospital |
| ||
| Tested PCR (+) for COVID-19, Severe - admitted to ICU (Intensive Care Unit) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Swab | Other | PCR test for SARS-CoV2, oral and nasal swab |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oral microbial signature | To assess the oral microbial signatures that relates to SARS-CoV2 in patients with no, mild and severe disease. | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Nasal microbial signature | To assess the nasal microbial signatures related to SARS-CoV2 in patients with no, mild and severe disease and to assess the role of the oral expression of ACE2-Ang II system during SARS-CoV2 in relation to disease outcome (mild, severe COVID). | Day 1 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
a. Under the age of 18 years old
Not provided
Not provided
Not provided
Adults who tested (PCR) positive or negative for SARS-CoV2 infection
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jeanie Suvan | Contact | +442034561108 | j.suvan@ucl.ac.uk |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University College Hospital (UCH), UCL Eastman Dental Institute | Recruiting | London | United Kingdom |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
Not provided
Not provided
Not provided
Not provided
Not provided
Oral and nasal swab
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |