Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease

Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease

This project is designed as a prospective, randomized, open, controlled clinical trial. For the first time, acupuncture was applied to the treatment of dry ocular neuropathic pain. Its mechanism was discussed by comparing the efficacy between acupuncture and artificial tears.

Inclusion Criteria:

• According to the DEWS diagnostic criteria, the OSDI score ≥ 13, with positive signs of dry eye (SIt ≤ 10mm/5min or TBUT ≤ 10s) or CFS positive;
• VAS>0;
• Signed informed consent.

Exclusion Criteria:

• Patients with dry eye who have had irritants directly irritating the ocular surface in the past 3 days;
• Eyeball infections, allergies, deformities, abnormal movements
• Any history of eye surgery
• Have had eye trauma or fundus laser treatment within 3 months
• Used drugs that affect tear production such as antihistamines, antidepressants, etc. within 30 days
• Suffer from systemic diseases that affect tear production, including Sjogren's syndrome, diabetes, mental illness, malignant tumors, etc.