Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution

Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 and Its Resolution

Prospective study to describe the immunological, metabolic and serologic profile in the acute and post acute phases of Coronavirus disease (COVID-19)

Inclusion Criteria for patients:

• adult patient
• Patient with Covid-19 confirmed by RT-PCR, supported by Poitiers hospital
• Patient came for RT-PCR test at the drive of the hospital, or hospitalised in one of the Covid-19 departments of the Poitiers hospital (geriatry, infectious and tropical diseases, medical resuscitation and continuous care unit)
• informed consent signed by the patient or a trusted or immediate person after clear and loyal information on the study

Exclusion Criteria for patients:

• minor patient
• patient having had syptoms for more than 8 days
• patient already enrolled in another study regarding immunomodulators
• patient not benefiting from a Social Security scheme or not benefiting from it through a third party
• patient benefiting from enhanced protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, adult under legal protection

Inclusion Criteria for volunteers:

• adult patient
• subject wishing to be vaccinated with anti-COVID-19 BioNTech Pfizer vaccine
• informed consent signed by the volunteer after clear and loyal information on the study

Exclusion Criteria for volunteers:

• minor patient
• subject having had COVID-19 documented by a positive RT-PCR test or serology
• subject already vaccinated against COVID-19 (complete or partial vaccinal scheme)
• patient not benefiting from a Social Security scheme or not benefiting from it through a third party
• patient benefiting from enhanced protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, adult under legal protection