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Low-frequency percutaneous electrical stimulation is the application of an electrical current of <1000Hz through acupuncture needles located on the epineurium of the peripheral nervous system.
The hypothesis is that by placing the electrode, needle, closer to the nerve, a greater stimulation of the same will be achieved, thus being able to obtain greater effects. The goal is to determine if this technique has any effect on grip strength in the short term.
Single-blind randomized clinical trial of n = 12 healthy subjects. 4 assessments of the grip strength of the non-dominant hand will be made using a digital dynamometer, by a blinded investigator. A V0-pre-intervention, a V1-post-intervention, a V2 at 24 hours and a V3 at 10 days after the intervention. Subjects will be randomly assigned by EPIDAT 3.1, to an experimental group or a control group, with n = 6 each group. In the experimental group, an ultrasound-guided percutaneous electrical stimulation will be performed. With a pointer, a symmetrical biphasic low-frequency current of 10 Hz and 240 microseconds will be applied to the median nerve and ulnar nerve, until reaching the excitomotor threshold, with applications of 10 seconds and rests of 5 seconds until reaching a stimulation of 1 minute. total over each nerve. In the control group, the same invasive procedure will be performed, but no type of electrical stimulation will be applied.
Statistical analysis will be performed by another blinded assessor, using IBM SPSS Statistics 24. A two-factor ANOVA (intervention-time) with Bonferroni correction will be performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental: 10 hz stimulatión | Experimental | Eco-guided percutaneous electrical stimulation application of low frequency electrical current at 10 hz, 240 microsecond, over the median and ulnar nerve in the arm, for 1 minute on each nerve. The intensity of the current will reach the excitomotor threshold, causing visible but comfortable contractions. |
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| Sham stimulation | Sham Comparator | Application of the needles only on the median and ulnar nerve of the arm, for 1 minute on each nerve without current intensity and a sound will be applied. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Eco-guided Percutaneous Electrical Stimulation | Device | Pointer 10 hz. A symetric, biphasic current of 10 hz and 240 microsecond. The stimulation intensity will be reaching the excitomotor threshold, producing visible but comfortable contractions. |
| Measure | Description | Time Frame |
|---|---|---|
| Hand-grip Strength | Muscle strength will be measured with a dynamometer and will be expressed in Kgs. | baseline at 0 minutes |
| Hand-grip Strength | Muscle strength will be measured with a dynamometer and will be expressed in Kgs. | Time Frame: immediately after intervention at 1 minute |
| Hand-grip Strength | Muscle strength will be measured with a dynamometer and will be expressed in Kgs. | Time Frame: 24 hours after intervention |
| Hand-grip Strength | Muscle strength will be measured with a dynamometer and will be expressed in Kgs. | Time Frame: 10 days after intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Juan AvendaƱo-Coy, PhD | Castilla-La Mancha University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Castilla-La Mancha University | Toledo | 45071 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35166034 | Derived | Alvarez DM, Serrano-Munoz D, Fernandez-Perez JJ, Moreno JS, Gomez-Soriano J, Avendano-Coy J. The effect on handgrip strength of low-frequency percutaneous electric stimulation applied to the median and cubital nerves: A randomized, double-blind controlled trial. Anat Rec (Hoboken). 2023 Apr;306(4):720-727. doi: 10.1002/ar.24887. Epub 2022 Feb 15. |
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| Sham stimulation | Device | Application of the needles only on the median and ulnar nerve of the arm, for 1 minute on each nerve without current intensity and applying a son. |
|