Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin

Comparative Study Between Analgesic Effect of Oral Prednisolone and Oral Pregabalin in Management of Post-dural Puncture Headache in Patients Undergoing Lower Limb Surgeries

The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects of prednisolone and pregabalin in patients undergoing lower limb surgery.

1. To compare between oral prednisolone and oral pregabalin in reducing severity post-dural puncture headache after spinal anesthesia in patients undergoing lower limb surgeries.
2. To calculate total amount of postoperative analgesic requirement for 72 hours after the onset of the headache in all patient groups.
3. To detect any side effects of the study medications in all patient groups.

Inclusion Criteria:

• - Both gender.
• Age: 18- 65 years old.
• Body Mass Index 20-30 kg/m2
• American Society of Anesthesiologist (ASA) physical status I - II.
• Patients are diagnosed as PDPH according to criteria of International Headache Society (IHS) after lower limb surgeries .

Exclusion Criteria:

• - Allergy to study drugs.
• History of chronic headache and migraine.
• History of cerebrovascular accidents and neurological disorders.
• Systemic infection
• History of uncontrolled DM or hepatic disease or pregnant female
• Patient refusal or uncooperative patient.