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The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry
The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| stimulated salivary flow rate | Experimental | stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Paraffin Pellets from Aurosan GmbH | Diagnostic Test | 1 to 2 minutes pre-chewing time chewing Paraffin Pellets from Aurosan GmbH, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes. |
| Measure | Description | Time Frame |
|---|---|---|
| Stimulated salivary flow rate (ml) | Comparing measurements of stimulated salivary flow rate (ml) after chewing two different chewing gums | at baseline (approx 40 minutes) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in consistency of chewing gum | Change in consistency (compressive strength, measured in Newton) of the chewing gums for stimulated salivary flow rate measurement over a time period of 7 minutes chewing time | at baseline (7 minutes for each chewing gum) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andreas Filippi, Prof | University Center for Dentistry Basel UZB | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Center for Dentistry Basel UZB | Basel | Canton of Basel-City | 4056 | Switzerland |
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| ID | Term |
|---|---|
| D014987 | Xerostomia |
| ID | Term |
|---|---|
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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Determination of salivary flow rate chewing Paraffin pellets (manufactured by Aurosan GmbH) for 7 minutes. At a later timepoint determination of salivary flow rate chewing Saliva-Check Buffer (manufactured by GC Europe) for 7 minutes.
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| Chewing wax from the Saliva-Check Buffer from GC Europe | Diagnostic Test | 1 to 2 minutes pre-chewing time chewing wax from the Saliva-Check Buffer from GC Europe, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes. |
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