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The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe, fulminating acute liver failure in the public hospitals of paris.
Severe, fulminating acute liver failure is a rare but serious disease. The overall prognosis has improved in recent years thanks to advances in medical management and liver transplantation.
However, the epidemiology of this disease in France, the survival with or without liver transplantation of these patients and the factors that can influence this survival are not well known.
The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe, fulminating acute liver failure in the public hospitals of paris (APHP).
The data will come from the APHP Health Data Warehouse
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| all patients diagnosed with a severe hepatic failure | Retrospective cohort using only data already entered in the Health data warehouse of the APHP (Public Paris Hospital) |
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| Measure | Description | Time Frame |
|---|---|---|
| The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe and fulminating acute hepatic failure within AP-HP hospitals | Patient status 1 month after diagnosis of this episode (alive or dead with or without transplantation) | 1 month from the diagnosis of this episode |
| Measure | Description | Time Frame |
|---|---|---|
| Epidemiology of Severe and fulminating acute hepatic failure | Sex Ratio M / F and cause of liver failure | Baseline |
| Cause of death | Cause of death |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with Severe liver failure or toxicants that may cause a liver failure
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Philippe ICHAI | Contact | 01 45 59 64 35 | philippe.ichai@aphp.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Paul Brousse Hospital | Villejuif | 94804 | France |
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| ID | Term |
|---|---|
| D017114 | Liver Failure, Acute |
| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| From date of inclusion until the date of death from any cause, assessed up to 9 years |
| Analysis of Clinical Pathway | Identification of the different services visited | up to 1month after the diagnosis of this episode |
| Reasons for new hospitalizations with an admission date within 6 months after the diagnosis this episode | Identification by the usual code of the new hospitalization, consecutive to the episode | within 6 months after the diagnosis this episode |