Preoperative i.v. Iron Substitution in Patients With Colon Cancer

Preoperative i.v. Iron Substitution in Patients With Colon Carcinoma and Iron-deficiency Anemia

About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb <130, female Hb <120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.

Randomized preoperative iron substitution for patient with iron deficient anemia

Inclusion Criteria:

• Age> 18 years
• Dg: Colon ca
• The planned measure: the colon resection
• Men: Hb <130, women: Hb <120 and iron deficiency (elevated TfR, low TrFesat or low ferritin)

Exclusion Criteria:

• hyperreactivity for Ferinject
• haemochromatosis
• refusal for participation