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| ID | Type | Description | Link |
|---|---|---|---|
| I7P-MC-DSAE | Other Identifier | Eli Lilly and Company |
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The main purpose of this study is to evaluate the safety and tolerability of LY3041658 in healthy participants. The study will measure how the body absorbs, breaks down and gets rid of LY3041658.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LY3041658 Low Dose | Experimental | LY3041658 administered by subcutaneous (SC) injection. |
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| LY3041658 High Dose | Experimental | LY3041658 administered by SC injection. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LY3041658 | Drug | Administered SC |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants With incidence and severity of Injection Site Reaction (ISR) | Number of Participants With incidence and severity of ISR | Baseline up to Day 15 |
| Visual Analog Scale (VAS) Score for Injection Site Pain | VAS Score for Injection Site Pain | Baseline up to Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY3041658 | PK: Cmax of LY3041658 | Predose up to day 85 postdose |
| PK: Area Under the Concentration Versus Time Curve (AUC) from time 0 to infinity of LY3041658 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) | Eli Lilly and Company | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lilly Centre for Clinical Pharmacology | Singapore | 138623 | Singapore |
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PK: AUC(0-inf) of LY3041658
| Predose up to day 85 postdose |