MSCs Therapy for Cerebral Palsy

Bone Marrow Stem Cells Transplantation for the Treatment of Cerebral Palsy

Cerebral palsy (CP) is the most common physical disability in childhood. CP comprises a heterogeneous group of disorders that are the result of a non-progressive disruption or injury that occurred during fetal brain development or within the first two years of life.

This disruption can result in spasticity, dystonia, muscle contractures, weakness and difficulty in coordination that ultimately affects the ability to control movements. Resultant activity limitations may affect gross motor movements, fine motor movements, speech and communication, as well as eating and drinking.

Inclusion Criteria:

• • Must be more than 2 year of age and less than 12 years of age at the time of screening for inclusion in the study.

  • Clinical evidence of a non-progressive motor disability due to brain dysfunction.

Exclusion Criteria:

• • Intractable seizures

  • Traumatic brain injury
  • Genetic disorder
  • Current Infection
  • Renal insufficiency
  • Hepatic disease
  • HIV+ (as demonstrated by positive blood test)
  • Immunosuppression