Research on the Effect and Mechanism of Aerobic Exercise on PD

Research on the Effect and Mechanism of Aerobic Exercise on Parkinson's

This trial is expected to recruit patients with primary Parkinson's disease and give them four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

This trial is expected to recruit patients with primary Parkinson's disease who are distributed into tremor group and stiff group and give them the same kind of four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

Inclusion Criteria:

• Participants were diagnosed primary PD according to the 2015 MDS diagnostic criteria
• Participants are between 55 and 65 years old

Exclusion Criteria:

• Severe heart
• liver dysfunction
• kidney dysfunction
• severe cognitive dysfunction
• severe anxiety and depression
• history of mental illness
• history of cerebral infarction or ischemic attack in the past three months
• acute myocardial infarction or acute coronary in the past three months
• Parkinson's Pulse syndrome
• medication history (drugs that improve blood circulation in the brain and increase the excitability of the nervous system)