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This is an epidemiology study for the prevalence and serotypes of pneumococcus pneumoniae in hospitalized patients with community acquired pneumonia (CAP). The serotypes of the pneumococcus pneumoniae will be determined by a urinary antigen assay. This is a single center, non-interventional observatory study.
Patients admitted to the medical wards with a provisional diagnosis under "pneumonia","chest infection" or "fever" will be screened by research assistants.
Patients eligible with the inclusion criteria will be recruited into the study. Informed consent will be signed for those patients willing to participate in the study. Patient will be asked to save approximately 40 ml of urine. The urine sample will be processed in local laboratory and shipped out to a commercial lab for detection of any pneumococcal pneumoniae, and if present, serotyping will be performed at the same time using the same urine sample by urinary antigen assay. Meanwhile patients will be managed as usual by their clinical teams. Investigations and treatment will be offered by the clinical team as deemed necessary. The study team will only perform collection of urine and will not interfere the clinical management of the patients.
Positive results would be informed to the clinical teams for the appropriate action.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CAP | community acquired pneumonia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| urine test | Diagnostic Test | test for pneumococcal antigen in urine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Determine the prevalence of pneumococcal serotypes in adults hospitalized | Determine the prevalence of pneumococcal serotypes in adults hospitalized with pneumococcal community acquired pneumonia (CAP) using a specific urine antigen assay | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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adults hospitalized with pneumococcal community acquired pneumonia (CAP)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| K W To | Contact | 55699297 | tokw617@yahoo.com.hk |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Medicine and Therapeutics, Prince of Wales Hospital, CUHK | Recruiting | Shatin | Hong Kong |
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| ID | Term |
|---|---|
| D000098968 | Community-Acquired Pneumonia |
| ID | Term |
|---|---|
| D017714 | Community-Acquired Infections |
| D007239 | Infections |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
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| ID | Term |
|---|---|
| D016482 | Urinalysis |
| ID | Term |
|---|---|
| D019963 | Clinical Chemistry Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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urine
| D012140 |
| Respiratory Tract Diseases |
| D003950 | Diagnostic Techniques, Urological |
| D008919 | Investigative Techniques |