Monitoring Strategies for the Detection of Atrial Fibrillation in Patients with Cryptogenic Stroke

48-hour Versus 7-day Monitoring for the Detection of Atrial Fibrillation in Patients with Cryptogenic Stroke

Randomized clinical trial comparing two monitoring strategies, the use of a 48-hour Holter (routine care branch) and an event recorder for 7 days (intervention branch).

Patients admitted for cryptogenic stroke will be included. Enrollment and randomization of patients will be carried out during the index case hospitalization, while follow-up will be done on an outpatient basis until day 7.

Once the diagnose of cryptogenic stroke have been carried out, informed consent will be taken and participants will be randomized to 48-hour monitoring arm or 7-day monitoring arm, followed by discharge from hospital.

Inclusion Criteria:

• All patients who have studies that classify stroke or TIA as cryptogenic and who can carry out monitoring for 48 hours or 7 days will be included.
• Age ≥ 18 years

Exclusion criteria

• History of atrial fibrillation (or atrial flutter) documented.
• Patients who already have an event recorder in place, permanent pacemaker, or implantable cardioverter-defibrillator
• Evidence of lacunar infarction.
• Hemorrhagic stroke
• Patient for palliative care