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| Name | Class |
|---|---|
| Fonds National de la Recherche Scientifique | OTHER |
| Université Catholique de Louvain | OTHER |
| Louvain Bionics, UCLouvain | UNKNOWN |
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To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).
Over 3 consecutive days, healthy individuals and chronic cerebellar stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan®.
They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks).
In addition, several "classical" clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...).
Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chronic Cerebellar Stroke | Experimental | Participants with a chronic cerebellar stroke |
|
| Healthy Individuals (Controls) | Active Comparator | healthy participants |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bimanual motor skill learning with the REAplan® rehabilitation robot | Device | REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in bi-SAT | Bimanual Speed/Accuracy Trade-off measured by the REAplan robot bimanual Speed/Accuracy Trade-off: mathematical computation of the relationship bewteen speed and accuracy | Change between day 1 to 3 |
| Change in bi-CO | Bimanual Coordination factor measured by the REAplan robot bimanual Coordination factor : mathematical measure of the phase coherence between velocities of both arms | Change between day 1 to 3 |
| Measure | Description | Time Frame |
|---|---|---|
| bi-SAT | On bimanual REACHING (REAplan robot) bimanual Speed/Accurady Trade-off: mathematical computation of the relationship | Day 1 + day 3 |
| bi-CO | On bimanual REACHING (REAplan robot) bimanual Coordination factor: mathematical measure of the phase coherence between velocities of both arms |
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STROKE PATIENTS:
Inclusion Criteria:
Exclusion Criteria:
HEALTHY INDIVIDUALS:
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yves Vandermeeren, MD, PhD | University Hospital of Mont-Godinne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU UCL Namur, Mont-Godinne, Neurology Department, Stroke Unit | Yvoir | Namur | 5530 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29326573 | Background | Yeganeh Doost M, Orban de Xivry JJ, Bihin B, Vandermeeren Y. Two Processes in Early Bimanual Motor Skill Learning. Front Hum Neurosci. 2017 Dec 20;11:618. doi: 10.3389/fnhum.2017.00618. eCollection 2017. | |
| 29420360 | Background | Dehem S, Gilliaux M, Lejeune T, Delaunois E, Mbonda P, Vandermeeren Y, Detrembleur C, Stoquart G. Effectiveness of a single session of dual-transcranial direct current stimulation in combination with upper limb robotic-assisted rehabilitation in chronic stroke patients: a randomized, double-blind, cross-over study. Int J Rehabil Res. 2018 Jun;41(2):138-145. doi: 10.1097/MRR.0000000000000274. |
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the precise IPD plan has to be worked out in order to find the best public repository
Up to 2 years after publication of the scientific articles
none (public)
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Evaluation of bimanual motor skill learning
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| Day 1 + day 3 |
| change in bi-Force | Bimanual forces : forces exerted in the wrong direction by each arm (Newtons) | Change between day 1 to 3 |
| bi-Force | On bimanual REACHING (REAplan robot) bimanual forces : forces exerted in the wrong direction by each arm (Newtons) | Day 1 + day 3 |
| bi-smoothness | On bimanual REACHING (REAplan robot) Smoothness of movement : Spectral Arc Length (SPARC) | Day 1+ day 3 |
| bi-error | on bimanual REACHING (REAplan robot) Error in centimeters or degrees during bimanual reaching | Day 1 + day 3 |
| Dextrain | Kinetic device measuring the movements of each finger: error and co-activation (percentage) | Day 1 + day 3 |
| Dextrain | Kinetic device measuring the movements of each finger: speed (milliseconds) | Day 1 + day 3 |
| Dextrain | Kinetic device measuring the movements of each finger: force (Newton) | Day 1 + day 3 |
| BBT | Box & Blocks Test (timed transfert of blocks from one space to the other) | Day 1 + day 3 |
| Modified International Cooperative Ataxia Rating Scale (MICARS) | Ataxia scale A high score describes strong ataxia and a low score describes weak ataxia | Day 1 |
| Fugl Meyer Upper extremity test | Tests impairments of the upper limb after stroke | Day 2 |
| Corsi block | Tests the visuo-spatial memory | Day 2 |
| Montreal Cognitive Assessment (MoCA) | Tests the short-term memory, visuospatial skills, executive functions, attention, concentration, working memory, language and orientation in time and space | Day 2 |
| Abilhand and activlim | Questionnaire about the bimanual hability during activities of the daily life | Day 3 |
| 31088342 | Background | Doost MY, Orban de Xivry JJ, Herman B, Vanthournhout L, Riga A, Bihin B, Jamart J, Laloux P, Raymackers JM, Vandermeeren Y. Learning a Bimanual Cooperative Skill in Chronic Stroke Under Noninvasive Brain Stimulation: A Randomized Controlled Trial. Neurorehabil Neural Repair. 2019 Jun;33(6):486-498. doi: 10.1177/1545968319847963. Epub 2019 May 15. |
| 38722346 | Derived | Gathy E, Cadiat N, Gerardin E, Lambert J, Herman B, Leeuwerck M, Bihin B, Vandermeeren Y. Bimanual coordinated motor skill learning in patients with a chronic cerebellar stroke. Exp Brain Res. 2024 Jun;242(6):1517-1531. doi: 10.1007/s00221-024-06830-x. Epub 2024 May 9. |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002526 | Cerebellar Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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