The primary aim of the current study is to assess the effect of continuous wireless vital sign monitoring with generation of real-time alerts, compared to blinded monitoring without alerts on the cumulative duration of any severely deviating vital signs in patients admitted to general hospital wards after major surgery.

We hypothesize that continuous vital signs monitoring, and real-time alerts will reduce the cumulative duration of severely deviating vital signs.

Inclusion Criteria:

• Admission for acute or elective major abdominal (laparotomy/laparoscopy), major orthopedic, major urologic, or arterial vascular surgery.
• Estimated duration of surgery ≥2 hours and at least two expected overnight stays.
• Randomization and commencement of continuous wireless monitoring possible within 24 hours postoperatively

Exclusion Criteria:

• Patient expected not to cooperate with study procedures.
• Allergy to plaster or silicone.
• Impaired cognitive function (in uncertain cases assessed by a Mini Mental State Examination] score < 24)
• Patients admitted for palliative care only (i.e. no active treatment).
• Planned admission to unit using continuous vital sign monitoring (i.e. an intermediary care/telemetry unit).
• Patients previously enrolled in the medical WARD RCT.
• Patients with a pacemaker or Implantable Cardioverter Defibrillator (ICD) device.
• Inability to give informed consent.