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| ID | Type | Description | Link |
|---|---|---|---|
| 2018-A03065-50 | Other Identifier | ID-RCB number, ANSM |
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Suicidal behaviors seriously alter the vital and functional prognosis of adolescents. Although the literature has lighted out a considerable number of risk factors for suicide attempts in youth, theoretical models - among which bio-psycho-social models - still lack empirical evidence. More specifically, the way adverse life events dynamically interact together and with the individual's diathesis to precipitate suicidal attempts remains unclear. Studies of life trajectories have opened an alternative approach to traditional linear epidemiological analysis to capture such a complex process. To date, adverse trajectories approaches never have been applied to the period immediately preceding the occurrence of the suicidal gesture (proximal adverse trajectories).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Suicide attempt cases | Adolescents and young adults who attempted suicide between 7 and 30 days prior the inclusion | ||
| Non-suicidal controls | Adolescents and young adults without history of suicide attempt or ideation |
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| Measure | Description | Time Frame |
|---|---|---|
| Growth parameters of the patterns of proximal adverse trajectories in adolescents who attempted suicide, as compared to non-suicidal adolescents | We will build growth mixture models to account for the 1-year longitudinal evolution of the Burden of Adversity values. Each group will be characterized by the parameters (intercepts and slopes) of the best-fitting model. We will the compare the parameters of the 2 groups to search for statistical differences | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Statistical tests comparing the sociodemographic, vulnerabily and psychopathological indicators between the sub-group of adolescents identified from the mixture model. | Growth mixture models will allow for identifying sub-groups of individuals who are similar as regards to their burden of adversity trajectories. We will compare the characteristics of theses subgroups | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Patient recruitment will be supported by the VigilanS program. VigilanS is a suicide recurrence prevention device implemented in all establishments in the Hauts-de-France region that receive patients who have attempted suicide (www.dispositifvigilans.org).
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| Name | Affiliation | Role |
|---|---|---|
| Charles-Edouard Notredame, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hop Fontan - Chu Lille | Lille | 59037 | France |
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| ID | Term |
|---|---|
| D013406 | Suicide, Attempted |
| ID | Term |
|---|---|
| D013405 | Suicide |
| D016728 | Self-Injurious Behavior |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Growth parameters of the patterns of evolution of psychological pain | Parallel to the burden of adversity growth models, we will build, for each group, growth models to predict the longitudinal evolution of psychological pain. We will then test whether the growth parameters of the ideation/pain trajectories correlate with those of the adversity trajectories | 1 year |
| Growth parameters of the patterns of evolution of suicidal ideation intensity | Parallel to the burden of adversity growth models, we will build, for each group, growth models to predict the longitudinal evolution of the severity of the suicidal ideations. We will then test whether the growth parameters of the ideation/pain trajectories correlate with those of the adversity trajectories | 1 year |