Fecal Microbiota Transplantation in Postoperative Crohn's Disease

Fecal Microbiota Transplantation in Postoperative Crohn's Disease

This pilot study aims to detect possible trends or signals suggesting efficacy of FMT on prevention of delay of POR, to determine the safety of FMT in post operative CD, and asses if a full randomised controlled trial is feasible in this setting. With microbiota analysis we aim to assess if changes in gut microbiota are related to disease course of CD after operation.

Inclusion Criteria:

• Over 18 years
• Able to provide written consent
• Stricturing and/or fistulizing Crohn's disease needing ileocecal or ileal resection

Exclusion Criteria:

• Pregnancy
• Active infection, abscess or fistula at the time of the first colonoscopy
• Life expectancy <1 year
• Unable to provide written consent
• Use on antibiotics or probiotics at the time of first colonoscopy