The Incidence and Risk Factors for Clostridioides Difficle Infection in Solid Organ Transplant Recipients

Everyone Poops: An Evaluation of the Incidence and Risk Factors for Clostridioides Difficle Infection in Solid Organ Transplant Recipients

2.1. Study Objectives

• Primary Objective(s)
• Identify the incidence and risk of CDI within one year after kidney, liver, and/or pancreas transplant
• Secondary Objective(s)
• Identify the risk factors for recurrent CDI post-transplant in patients who were diagnosed with a CDI within one year prior to Solid Organ Transplant
• Evaluate the impact of CDI on graft survival following Solid Organ Transplant

• Single center, retrospective cohort chart review study design
• Data will be collected on all liver, kidney, pancreas and combined transplant recipients who received their graft(s) from April 1, 2015 to July 31, 2018
• Will analyze outcomes from April 1, 2014 to July 31, 2019
• Patient list will be generated in Epic and Meditech
• All data will be obtained from Epic and Meditech
• All data will be collected retrospectively after the patient is discharged from the hospital

Inclusion Criteria:

• Solid organ transplant patients who received graft(s) at MDMC from April 1, 2015 to July 31, 2018
• Age >18 years old

Exclusion Criteria:

• Age <18 years old
• Loss to early death defined as within one week from transplantation
• Patients whose primary address is in Puerto Rico