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To compare the effect of IPL combined with lipiflow and IPL combined with meibomian gland massage in treating meibomian gland dysfunction of different degrees ,focusing on effective rate, lasting time and changes of meibomian gland function and morphology.
To divide all participants into two groups, group one treated with IPL combined with Lipiflow and group two treated with IPL combined with meibomian gland massage.The following parameters were recorded after treatment: the effective rate, lasting time and changes of meibomian gland function and morphology.All parameters were compared between the two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IPL/Lipiflow | Experimental | the group in which patients treated with IPL combined with lipiflow |
|
| IPL/MGX | Active Comparator | the group in which patients treated with IPL combined with meibomian gland massage |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IPL/Lipiflow | Procedure | To treat patients with MGD using intense pulsed light combined with lipiflow |
|
| Measure | Description | Time Frame |
|---|---|---|
| ocular surface disease index(OSDI) | The OSDI is assessed on a scale of 0 to 100,with higher scores representing greater disability | 6 months |
| meibomian gland expressibility score and meibum quality score | The score is on a scale of 0 to 6.The higher scores, the severity of the meibomian gland function(the highest score is 6 and the lowest score is 0) | 6 months |
| meibomian gland dropout score | the higher scores, the severity of the meibomian gland morphology(The highest score is 6 and the lowest score is 0) | 6 months |
| Breakup time | the shorter time, the poorer of the tear film stability | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yan Chen, doctor | Contact | +86-021-62956699 | chinacy@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Yan Chen, doctor | Shanghai aier eys hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D000080343 | Meibomian Gland Dysfunction |
| ID | Term |
|---|---|
| D005141 | Eyelid Diseases |
| D005128 | Eye Diseases |
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| IPL/MGX | Procedure | To treat patients with MGD using intense pulsed light combined with meibomian gland massage |
|